Merck
  • 880120C
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880120C

Avanti

18:0 PEG2000 PE

Avanti Polar Lipids 880120C

Synonym(s):
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
CAS Number:
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880120C-25mg)
pkg of 1 × 20 mL (880120C-500mg)
pkg of 2 × 4 mL (880120C-200mg)

manufacturer/tradename

Avanti Polar Lipids 880120C

concentration

10 mg/mL (880120C-25mg)
25 mg/mL (880120C-200mg)
25 mg/mL (880120C-500mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

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18:0 PEG2000 PE Avanti Polar Lipids 880120C

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880120P

18:0 PEG2000 PE

18:0 PEG1000 PE Avanti Polar Lipids 880720C

Avanti

880720C

18:0 PEG1000 PE

form

liquid

form

liquid

form

powder

form

liquid

packaging

pkg of 1 × 2.5 mL (880120C-25mg), pkg of 1 × 20 mL (880120C-500mg), pkg of 2 × 4 mL (880120C-200mg)

packaging

pkg of 1 × 2.5 mL (880220C-25mg), pkg of 1 × 20 mL (880220C-500mg)

packaging

pkg of 1 × 1 g (880120P-1g), pkg of 1 × 200 mg (880120P-200mg), pkg of 1 × 25 mg (880120P-25mg), pkg of 1 × 500 mg (880120P-500mg)

packaging

pkg of 1 × 2.5 mL (880720C-25mg), pkg of 2 × 4 mL (880720C-200mg)

manufacturer/tradename

Avanti Polar Lipids 880120C

manufacturer/tradename

Avanti Polar Lipids 880220C

manufacturer/tradename

Avanti Polar Lipids 880120P

manufacturer/tradename

Avanti Polar Lipids 880720C

concentration

10 mg/mL (880120C-25mg), 25 mg/mL (880120C-200mg), 25 mg/mL (880120C-500mg)

concentration

10 mg/mL (880220C-25mg), 25 mg/mL (880220C-500mg)

concentration

-

concentration

10 mg/mL (880720C-25mg), 25 mg/mL (880720C-200mg)

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

18:0 PEG2000 PE, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000], is a modified phospholipid containing a 2000-Da PEG moiety in the polar head.

Application

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt (DSPE-PEG1) has been used to conjugate PEG onto residual amine groups on the surfaces of the functionalized TaO nanoparticles. DSPE-PEG1 may be used as a surfactant for homeotropic anchoring of the mesogen molecules. It may also be used in preparation of Nano formulations.

Biochem/physiol Actions

PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to facilitate the formation of sterically stabilized liposomes (SSL). These liposomes have low reticuloendothelial system (RES) uptake and they prolong the circulating plasma half-life of the drug. The plasma half-life of the drug can be tuned from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880120C-500mg)
5 mL Clear Glass Sealed Ampule (880120C-200mg)
5 mL Clear Glass Sealed Ampule (880120C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

880120C-500MG:4.548173349114E12
880120C-25MG:4.548173349107E12


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