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880410C

Avanti

14:0 PEG350 PE

Avanti Polar Lipids 880410C

Synonym(s):
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] (ammonium salt)
CAS Number:
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880410C-25mg)

manufacturer/tradename

Avanti Polar Lipids 880410C

concentration

10 mg/mL (880410C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

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14:0 PEG350 PE Avanti Polar Lipids 880410C

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880410C

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14:0 PEG3000 PE Avanti Polar Lipids 880310C

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14:0 PEG750 PE Avanti Polar Lipids 880610P, powder

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880610P

14:0 PEG750 PE

14:0 PEG550 PE Avanti Polar Lipids 880510P, powder

Avanti

880510P

14:0 PEG550 PE

packaging

pkg of 1 × 2.5 mL (880410C-25mg)

packaging

pkg of 1 × 2.5 mL (880310C-25mg)

packaging

pkg of 1 × 25 mg (880610P-25mg)

packaging

pkg of 1 × 25 mg (880510P-25mg)

manufacturer/tradename

Avanti Polar Lipids 880410C

manufacturer/tradename

Avanti Polar Lipids 880310C

manufacturer/tradename

Avanti Polar Lipids 880610P

manufacturer/tradename

Avanti Polar Lipids 880510P

concentration

10 mg/mL (880410C-25mg)

concentration

10 mg/mL (880310C-25mg)

concentration

-

concentration

-

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

14:0 PEG350 PE is a polyethylene glycol (PEG) conjugated phospholipid. PEGylated phospholipids are amphiphilic polymers.
Poly (ethylene glycol)s (PEGs)- phosphatidylethanolamines (PEs) lipids are anionic double tailed lipids. Its structure contains a wedge shaped bulky hydrophilic polar head.

Application

14:0 PEG350 PE is suitable for use in the preparation of floating bilayer lipid membrane to mimic the environment of a biological cell membrane.

Biochem/physiol Actions

Liposome formulation commonly incorporates polyethylene glycol (PEG) conjugated phospholipids, as they efficiently maintain their stereochemistry. They are also used as drug carriers. The formation of mixed micelles is supported by the use of highly concentrated PEG-lipids.
Poly (ethylene glycol)s (PEGs)- phosphatidylethanolamines (PEs) lipids are key constituents of sterically stabilized liposomes, which are used as drug vehicles.

Packaging

5 mL Clear Glass Sealed Ampule (880410C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names


Certificates of Analysis (COA)

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Micro- and Nanoengineering of the Cell Surface (2014)
Rosa Bartucci et al.
Chemistry and physics of lipids, 124(2), 111-122 (2003-06-24)
Conventional electron spin resonance (ESR) spectroscopy of different positional isomers of phosphatidylcholine spin labels (n-PCSL; n=5, 7, 10, 12, 14, and 16) has been used to study micellar dispersions made of poly(ethylene glycol)s-phosphatidylethanolamines (PEGs-PEs) polymer-lipids. Such aggregates are currently used
Electrochemical and PM-IRRAS studies of floating lipid bilayers assembled at the Au (111) electrode pre-modified with a hydrophilic monolayer
Su Z, et al.
Journal of Electroanalytical Chemistry, 688, 76-85 (2013)
Sirkku Hanski et al.
Biomacromolecules, 11(12), 3440-3447 (2010-10-27)
We report on highly ordered oblique self-assemblies in ionic complexes of PEGylated triple-tail lipids and cationic polypeptides, as directed by side-chain crystallization, demonstrating also reversible oblique-to-hexagonal order-order transitions upon melting of the side chains. This is achieved in bulk by
G F Peacock et al.
Drug delivery, 10(1), 29-34 (2003-01-30)
A new cholesterol-carborane conjugate (BCH) has been synthesized as a potential targeting agent for boron neutron capture therapy (BNCT) of cancers. The compound is extremely water insoluble and was formulated in two liposomal formulations to determine if the compound could

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