Merck
All Photos(1)

890898P

Avanti

DOTMA

Avanti Polar Lipids

Synonym(s):
1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt)
Empirical Formula (Hill Notation):
C42H84ClNO2
CAS Number:
Molecular Weight:
670.57
NACRES:
NA.25

form

powder

packaging

pkg of 2 × 100 mg (890898P-200mg)
pkg of 1 × 25 mg (890898P-25mg)

manufacturer/tradename

Avanti Polar Lipids

application(s)

advanced drug delivery

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC.[Cl-]

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DOTMA Avanti Polar Lipids

Avanti

890898P

DOTMA

DOTMA Avanti Polar Lipids 890898C

Avanti

890898C

DOTMA

DODMA Avanti Polar Lipids

Avanti

890899C

DODMA

DMG-PEG 2000 Avanti Polar Lipids

Avanti

880151P

DMG-PEG 2000

form

powder

form

liquid

form

chloroform solution

form

powder

packaging

pkg of 2 × 100 mg (890898P-200mg), pkg of 1 × 25 mg (890898P-25mg)

packaging

pkg of 1 × 2.5 mL (890898C-25mg), pkg of 2 × 4 mL (890898C-200mg)

packaging

pkg of 1 × 4 mL (890899C-100MG), pkg of 5 × 4 mL (890899C-500MG)

packaging

pkg of 1 × 1 g (880151P-1G), pkg of 1 × 5 g (880151P-5G)

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids 890898C

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

application(s)

advanced drug delivery

application(s)

advanced drug delivery

application(s)

advanced drug delivery

application(s)

advanced drug delivery

Application

DOTMA is suitable for use as a building block of miRNA delivery system and in the preparation.

Biochem/physiol Actions

DOTMA is a cationic lipid, used as a non-viral vector for gene therapy. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome - cell membrane interaction.

Packaging

5 mL Clear Glass Sealed Ampule (890898P-200mg)
5 mL Clear Glass Sealed Ampule (890898P-25mg)

Storage Class Code

13 - Non Combustible Solids


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