Merck
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GF171

Sigma-Aldrich

Endostatin Protein, Human Recombinant

The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.

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Synonym(s):
Collagen Type XVIII, Collagen alpha-1 (XVIII)
eCl@ss:
32160405
NACRES:
NA.75

recombinant

expressed in E. coli

Quality Level

Assay

>98% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

UniProt accession no.

shipped in

dry ice

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This Item
GF316GF144ABC60
assay

>98% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE)

assay

-

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 ng/μg Endotoxin (of EGF; 1EU/μg)

impurities

-

UniProt accession no.

P39060

UniProt accession no.

P01133

UniProt accession no.

P01133

UniProt accession no.

P39061

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

General description

Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
Product Source: E. coli.

Specificity

Cross Reactivty
None

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Quality

Bioactivity assay: Measured by its ability to inhibit HUVEC migration.

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.

Storage and Stability

Store at -20°C for up to 6 months from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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