Merck
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SKBM02560

Millipore

PES Membrane Filter

Strat-M®, filter diam. 25 mm

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Synonym(s):
PES membrane for transdermal diffusion testing, Polyethersulfone Strat-M membrane, Strat-M® Membrane, Transdermal Diffusion Test Model, 25mm
eCl@ss:
32160907
NACRES:
NB.24

material

plain filter
polyethersulfone membrane (synthetic lipid post-treatment)
polyolefin membrane (synthetic lipid post-treatment)
white filter

Quality Level

sterility

non-sterile

manufacturer/tradename

Millipore
Strat-M®

filter diam.

25 mm

thickness

300 μm

shipped in

ambient

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1 of 4

This Item
SKBM04760GVWP02500GVWP09050
PES Membrane Filter Strat-M®, filter diam. 25 mm

Millipore

SKBM02560

PES Membrane Filter

PES Membrane Filter Strat-M®, filter diam. 47 mm

Millipore

SKBM04760

PES Membrane Filter

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

manufacturer/tradename

Millipore, Strat-M®

manufacturer/tradename

Millipore, Strat-M®

manufacturer/tradename

Durapore®, Millipore

manufacturer/tradename

Durapore®, Millipore

filter diam.

25 mm

filter diam.

47 mm

filter diam.

25 mm

filter diam.

90 mm

thickness

300 μm

thickness

300 μm

thickness

125 μm

thickness

125 μm

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

General description

Filter Code: SKBM
Strat-M Membrane for Transdermal Diffusion Testing
Experience the unmatched predictability of Strat-M membrane – a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Strat-M membrane is designed for screening of:
•Active pharmaceutical ingredients (API)
•Cosmetic actives
•Formulations
•Personal care products
•Pesticides and chemicals

Human Skin Correlation
Strat-M membrane is predictive of diffusion in human skin for a wide range of compounds and formulations. Use the Compound Correlation Tool to learn how well Strat-M membrane will work for you.

Reproducible Diffusion Data:
No need to repeat testing each time a new lot of skin arrives in the lab. Strat-M membrane is a highly consistent, engineered material that allows you to compare today’s diffusion data with data you will generate next week, or next month. Furthermore, lot-to-lot consistency brings a new level of clarity to your test data, simplifying your analysis.

Sensitive to Enhancers
Strat-M membrane exhibits differential permeability in the presence of enhancers and is compatible with common formulation formats, so it is appropriate for use during formulation optimization.

Ultimate Experimental Convenience
Strat-M membrane was designed with convenience in mind. The Strat-M membrane is shelf-stable and stocked in the warehouse so procurement and storage is a breeze. Each membrane is individually packaged as precut discs and do not need to be hydrated prior to use. Simply remove the Strat-M membrane disc from its pouch and load into a Franz cell.

Application

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

Legal Information

STRAT-M is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

IN VITRO SKIN MODELS AS A TOOL IN OPTIMIZATION OF DRUG FORMULATION.
Flaten GE, Palac Z, Engesland A, Filipovic-Grcic J, Vanic Z, Skalko-Basnet N
European Journal of Pharmaceutical Sciences null
A REVIEW OF THE CURRENT STATE OF THE ART OF PHYSIOLOGICALLY-BASED TESTS FOR MEASURING HUMAN DERMAL IN VITRO BIOAVAILABILITY OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) IN SOIL
Beriro DJ, Cave MR, Wragg J, Thomas R, Wills G, Evans F.
Journal of Hazardous Materials null
Membrane properties for permeability testing: Skin versus synthetic membranes
Haq A, Dorrani M, Goodyear B, Joshi V, Michniak-Kohn B.
International Journal of Pharmaceutics null
IMPACT OF DIFFERENT VEHICLES FOR LASER-ASSISTED DRUG PERMEATION VIA SKIN: FULL-SURFACE VERSUS FRACTIONAL ABLATION.
Lee WR, Shen SC, Aljuffali IA, Li YC, Fang JY.
Pharmaceutical Research null
PREDICTION OF SKIN PERMEATION BY CHEMICAL COMPOUNDS USING THE ARTIFICIAL MEMBRANE, STRAT-M?
Uchida T, Kadhum WR, Kanai S, Todo H, Oshizaka T, Sugibayashi K
European Journal of Pharmaceutical Sciences null

Articles

Substituting Strat-M® Membrane for Human Skin in Evaluating Effect of Encapsulation on Diffusion of Sunscreen Formulations

Understand how a Strat-M synthetic membrane model can be an alternative to human or animal skin when screening for effectiveness of encapsulation on reducing transdermal diffusion of skin care actives

Protocols

Transdermal Diffusion Testing with Strat-M® Synthetic Skin Membranes using Franz Diffusion Cell Systems

Step-by-step protocol and video for transdermal diffusion testing using Strat-M® synthetic skin membranes.

Protocol for In-vitro Permeation Testing Using Strat-M® Membranes

Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

Related Content

Strat-M® Transdermal Diffusion Membrane

Strat-M® membrane is a reliable, engineered transdermal diffusion testing material that allows you to compare today’s diffusion data with data from next week – or even next month. Lot-to-lot consistency brings a new level of clarity to your data, simplifying your design and analysis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service