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14606

Cholesterol

tested according to Ph. Eur.

Synonym(s):

Cholesterolum, 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol

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Size/SKUAvailabilityPrice
100 g
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¥66,300

About This Item

Empirical Formula (Hill Notation):
C27H46O
CAS Number:
Molecular Weight:
386.65
UNSPSC Code:
41141804
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-353-2
Beilstein/REAXYS Number:
1915888
MDL number:

¥66,300


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Quality Segment

agency

tested according to Ph. Eur.

form

powder

bp

360 °C (lit.)

mp

147-149 °C (lit.)

solubility

chloroform: soluble 1 gm in 4.5 ml, diethyl ether: soluble 1 gm in 2.8 ml, pyridine: soluble 1 gm in 1.5 ml, H2O: insoluble, acetone: soluble, alcohol: slightly soluble, alcohol: very soluble (Hot), benzene: soluble, dioxane: soluble, ethyl acetate: soluble, hexane: soluble, oil: soluble, petroleum ether: soluble

density

1.067 g/mL at 25 °C (lit.)

application(s)

research use (small molecule)

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

HVYWMOMLDIMFJA-DPAQBDIFSA-N

Gene Information

Application

Cholesterol was used for preparing ISCOMS containing ovalbumin (OVA) for studying whether the incorporation of the protein antigen ovalbumin (OVA) in lipophilic immune-stimulating complexes (ISCOMS) induces very strong primary immune responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

Biochem/physiol Actions

Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.
Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

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This Item
C8503H6167C3045
description

tested according to Ph. Eur.

description

from sheep wool, ≥92.5% (GC), powder

description

from sheep wool, Controlled origin, meets USP/NF testing specifications

description

powder, BioReagent, suitable for cell culture, ≥99%

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

room temp

storage temp.

room temp

storage temp.

−20°C

solubility

hexane: soluble, acetone: soluble, pyridine: soluble 1 gm in 1.5 ml, chloroform: soluble 1 gm in 4.5 ml, alcohol: slightly soluble, benzene: soluble, oil: soluble, H2O: insoluble, diethyl ether: soluble 1 gm in 2.8 ml, petroleum ether: soluble, ethyl acetate: soluble, alcohol: very soluble (Hot), dioxane: soluble

solubility

water: soluble 0.00003 g/L at 20 °C

solubility

water: soluble 0.00003 g/L at 20 °C

solubility

serum: soluble, Tween: soluble, ethanol: soluble, H2O: 0.002 mg/mL

density

1.067 g/mL at 25 °C (lit.)

density

1.067 g/mL at 25 °C (lit.)

density

1.067 g/mL at 25 °C (lit.)

density

1.067 g/mL at 25 °C (lit.)

mp

147-149 °C (lit.)

mp

147-149 °C (lit.)

mp

147-149 °C (lit.)

mp

147-149 °C (lit.)

bp

360 °C (lit.)

bp

360 °C (lit.)

bp

360 °C (lit.)

bp

360 °C (lit.)


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Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

14606-100G-F: + 14606-BULK-F: + 14606-VAR-F:

jan



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Dear Madam or Sir, can you please tell me what is the purity grade of this cholesterol batch? Unfortunately, I could not find it on your website. Thank you.

    1 answer
    1. The exact purity value is listed on the lot specific Certificate of Analysis. Please navigate to the DOCUMENTATION part of the Product Detail Page to access a certificate under ‘Certificate of Analysis’: https://www.sigmaaldrich.com/product/sial/14606#product-documentation

      Helpful?

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