L-Isoleucine

Name: <SC>L</SC>-Isoleucine
Brand: SIAL
Price: 23400 JPY

certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(s):

(2S,3S)-2-Amino-3-methylpentanoic acid

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100 MG

¥23,400

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About This Item

Linear Formula:

C₂H₅CH(CH₃)CH(NH₂)CO₂H

CAS Number:

73-32-5

Molecular Weight:

131.17

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329758192

EC Number:

200-798-2

Beilstein/REAXYS Number:

1721792

MDL number:

MFCD00064222

Key Documents

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Product Name

L-Isoleucine, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

SMILES string

CC[C@H](C)[C@H](N)C(O)=O

InChI key

AGPKZVBTJJNPAG-WHFBIAKZSA-N

grade

certified reference material
TraceCERT^®

product line

TraceCERT^®

analyte chemical class(es)

amino acids, peptides, proteins

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

mp

288 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

Quality Level

300

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Related Categories

Amino Acid, Peptide & Protein Standards

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Show Differences

1 of 4

This Item	PHR1099	1349502	W527602
Supelco 56241 L-Isoleucine	Supelco PHR1099 L-Isoleucine	USP 1349502 L-Isoleucine	Sigma-Aldrich W527602 L-Isoleucine
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) -
application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) flavors and fragrances
format neat	format neat	format neat	format -
Quality Level 300	Quality Level 300	Quality Level -	Quality Level 400
grade certified reference material, TraceCERT^®	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard	grade FG
manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	manufacturer/tradename -	manufacturer/tradename USP	manufacturer/tradename -

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out the entire portfolio of our amino acids certified reference materials (CRM)

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Long-term leisure-time physical activity and serum metabolome.

Urho M Kujala et al.

Circulation, 127(3), 340-348 (2012-12-22)

Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk. Sixteen same-sex twin pairs (mean age, 60 years) were selected

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.

Anna L Vestergaard et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(14), E1334-E1343 (2014-04-08)

P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet, upholding an essential membrane asymmetry. The mechanism of flipping this giant substrate has remained an enigma. We have investigated the

Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise.

Eva Blomstrand et al.

The Journal of nutrition, 136(1 Suppl), 269S-273S (2005-12-21)

BCAAs (leucine, isoleucine, and valine), particularly leucine, have anabolic effects on protein metabolism by increasing the rate of protein synthesis and decreasing the rate of protein degradation in resting human muscle. Also, during recovery from endurance exercise, BCAAs were found

Innervation and effects of dilatory neuropeptides on cerebral vessels. New aspects.

L Edvinsson

Blood vessels, 28(1-3), 35-45 (1991-01-01)

The cerebral circulation is supplied with two vasodilator systems: the parasympathetic system storing vasoactive intestinal peptide, peptide histidine isoleucine, acetylcholine and in a subpopulation of nerves neuropeptide Y, and the sensory system, mainly originating in the trigeminal ganglion, storing substance

Amino acid mutagenesis of the ligand binding site and the dimer interface of the metabotropic glutamate receptor 1. Identification of crucial residues for setting the activated state.

Toshihiro Sato et al.

The Journal of biological chemistry, 278(6), 4314-4321 (2002-11-22)

Previously, we determined the crystal structures of the dimeric ligand binding region of the metabotropic glutamate receptor subtype 1. Each protomer binds l-glutamate within the crevice between the LB1 and LB2 domains. We proposed that the two different conformations of

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