This Item	A5611	A2153	A3803
Sigma-Aldrich A2514 Albumin from goat	Sigma-Aldrich A5611 Bovine Serum Albumin	Sigma-Aldrich A2153 Bovine Serum Albumin	$Bovine Serum Albumin heat shock fraction, lyophilized powder, essentially fatty acid free, ≥98% (agarose gel electrophoresis)$ Sigma-Aldrich A3803 Bovine Serum Albumin
biological source goat	biological source bovine	biological source bovine	biological source bovine
assay ≥96% (agarose gel electrophoresis)	assay ≥96% (agarose gel electrophoresis)	assay ≥96% (agarose gel electrophoresis)	assay ≥98% (agarose gel electrophoresis)
Quality Level 300	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

General description

Albumin is a globular protein. Serum albumin is a member of the multigene protein family. Human serum albumin (HSA) consists of three homologous domains (I-III) that form a heart-shaped structure. Each domain is a result of two subdomains called A and B. Bovine serum albumin (BSA) has a structure that is very similar to HSA as it has a heart-shaped structure that has three homologous domains (I-III) and each domain has three sub-domains.

Application

Albumin from goat has been used to verify the specificity of radioimmunoassay (RIA)-780 and 805.

Biochem/physiol Actions

Albumin is a highly soluble, multifunctional and major circulating plasma protein. It plays a role in physiological and pharmacological areas. Albumin participates in the transport of metals, cholesterol, hormones, bile pigments, drugs, and fatty acids. It regulates osmotic pressure and distributes fluids between various compartments. In addition, plasma albumin exhibits anti-oxidant effects to minimize oxidative stress. Albumin attributes to the major portion of total serum antioxidant properties.

Preparation Note

Fraction V Powder

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

A2514-5G:
A2514-BULK:
A2514-1G:
A2514-250MG:
A2514-100MG:
A2514-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number

0000466099

0000450989

0000450988

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Chimeric IgG4 PR3-ANCA induces selective inflammatory responses from neutrophils through engagement of Fcgamma receptors.

Abdullah Hussain et al.

Immunology, 128(2), 236-244 (2009-09-11)

Anti-proteinase 3 antibodies are implicated in the pathogenesis of small vessel vasculitis. These are primarily immunoglobulin G (IgG), with different subclasses predominating at different stages of disease. However, little is known of their respective roles in pathogenesis. We have previously

Iodixanol, constriction of medullary descending vasa recta, and risk for contrast medium-induced nephropathy.

Mauricio Sendeski et al.

Radiology, 251(3), 697-704 (2009-04-16)

To determine whether a type of contrast medium (CM), iodixanol, modifies outer medullary descending vasa recta (DVR) vasoreactivity and nitric oxide (NO) production in isolated microperfused DVR. Animal handling conformed to the Animal Care Committee Guidelines of all participating institutions.

Effect of thermal denaturation, inhibition, and cleavage of disulfide bonds on the low-frequency Raman and FTIR spectra of chymotrypsin and albumin.

Nikolay N Brandt et al.

Journal of biomedical optics, 20(5), 051015-051015 (2014-12-06)

The analysis of the structure-function relationship is extremely important in the study of proteins. The importance of function-related motions of large parts or subglobules of protein molecules stimulates the spectroscopic study in the low-frequency (terahertz) domain. However, only tentative assignments

A dual component heme biosensor that integrates heme transport and synthesis in bacteria.

Christopher L Nobles et al.

Journal of microbiological methods, 118, 7-17 (2015-08-09)

Bacterial pathogens acquire host iron to power cellular processes and replication. Heme, an iron-containing cofactor bound to hemoglobin, is scavenged by bacterial proteins to attain iron. Methods to measure intracellular heme are laborious, involve complex chemistry, or require radioactivity. Such

Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity.

Claus G Madsen et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 92, 1-7 (2015-02-11)

This study describes how protein release from polymer matrices correlate with simple measurements on the intrinsic viscosity of the polymer solutions used for casting the matrices and calculations of the solubility parameters of polymers and solvents used. Matrices of poly(dl-lactide-co-glycolide)

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Albumin from goat

≥96% (agarose gel electrophoresis)

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¥47,000

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