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P2256

Sigma-Aldrich

Sodium pyruvate

ReagentPlus®, ≥99%

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Synonym(s):
α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
Linear Formula:
CH3COCOONa
CAS Number:
Molecular Weight:
110.04
Beilstein:
3568341
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

product line

ReagentPlus®

Assay

≥99%

form

powder

loss

≤0.5% loss on drying

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL, clear, colorless to faintly yellow

cation traces

heavy metals (as Pb): ≤20 ppm

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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Sodium pyruvate BioXtra, ≥99%

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Premium Grade
solubility

H2O: 100 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 1 M, clear, colorless

assay

≥99%

assay

≥99%

assay

≥99%

assay

≥99%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

cation traces

heavy metals (as Pb): ≤20 ppm

cation traces

-

cation traces

heavy metals (as Pb): ≤20 ppm

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005%

General description

Sodium pyruvate (SP) is a simplest keto-acid. It crystallizes as very thin plates and belongs to the monoclinic system. Its utility in Knoevenagel condensation carried out in an aqueous medium has been examined. The standard molar enthalpy of formation and molar enthalpy of dissolution of SP at infinite dilution have been obtained. Its efficacy in treating mitochondrial DNA depletion syndromes has been investigated.

Application

Sodium pyruvate has been used:
  • To prepare Bull Tyrode′s albumin-lactate-pyruvate diluent.
  • In pyruvate tolerance test.
  • To prepare oligodendrocyte culture medium.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Crystal structure and thermochemical properties of a novel coordination compound sodium pyruvate C3H3O3Na(s).
Gao ZF, et al.
The Journal of Chemical Thermodynamics, 78, 189-196 (2014)
The crystal structure of sodium pyruvate.
Tavale SS, et al.
Acta Crystallographica, 14(12), 1281-1286 (1961)
"On Water": Rapid Knoevenagel Condensation Using Sodium Pyruvate.
Heravi MM, et al.
Letters in Organic Chemistry, 3(4), 297-299 (2006)
Pyruvate therapy for mitochondrial DNA depletion syndrome.
Saito K, et al.
Biochim. Biophys. Acta Gen. Subj., 1820(5), 632-636 (2012)

Protocols

This procedure applies to all products from heart muscle that have a specification for L-Lactic Dehydrogenase activity.

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