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A4503

Sigma-Aldrich

Bovine Serum Albumin

cold ethanol fraction, pH 5.2, ≥96%

Synonym(s):

Albumin bovine serum, BSA, Bovine albumin

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10 G
¥23,200
50 G
¥66,400
100 G
¥116,000
500 G
¥402,000
1 KG
¥591,000

¥23,200


Estimated to ship onMarch 05, 2026From市川市大町368



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10 G
¥23,200
50 G
¥66,400
100 G
¥116,000
500 G
¥402,000
1 KG
¥591,000

About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.27

¥23,200


Estimated to ship onMarch 05, 2026From市川市大町368


biological source

bovine

Quality Level

Assay

≥96%

form

lyophilized powder

mol wt

~66 kDa

purified by

cold ethanol fractionation

origin

USA origin

technique(s)

ELISA: suitable
blood typing: suitable
microbiological culture: suitable

impurities

BT and VSV virus, tested

loss

≤5%

pH

5.2

solubility

water: soluble (40 mg/ml)

UniProt accession no.

foreign activity

BT Virus, none detected
VSV Virus, none detected

storage temp.

2-8°C

Gene Information

bovine ... ALB(280717)

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1 of 4

This Item
A3912A38032905-OP
assay

≥96%

assay

≥96%

assay

≥98% (agarose gel electrophoresis)

assay

≥99±% (electrophoresis)

technique(s)

ELISA: suitable, microbiological culture: suitable, blood typing: suitable

technique(s)

blood typing: suitable, microbiological culture: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

origin

USA origin

origin

USA origin

origin

USA origin

origin

-

biological source

bovine

biological source

bovine

biological source

bovine

biological source

-

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

100

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

Bovine serum albumin is a model protein in various studies and is made up of 583 amino acids.[1][2] It is a water-soluble protein with a molecular weight of 66.4kDa. Six α-helices form three homologous domains of BSA. Depending on pH, it undergoes reversible conformational isomerization. The native structure of the protein becomes reactive and flexible on heating.[3]

Application

  • Bovine Serum Albumin has been used in solution prepared for the isolation of heart mitochondria.[4]
  • It has been used in the cytotoxicity assay buffer.[5]
  • It has been used for the induction of protein overload nephropathy in rats.[6]

Biochem/physiol Actions

Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.

Preparation Note

Often referred to as Cohn fraction V; this product is prepared by a modified method of the Cohn cold ethanol fractionation method.
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

A4503-100G:
A4503-VAR:
A4503-5G:
A4503-BULK:
A4503-10G:
A4503-50G:
A4503-1KG:
A4503-5KG:
A4503-500G:
A4503-10KG:


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