A8185

Ala-Gln

BioReagent, suitable for cell culture, suitable for insect cell culture

• Synonym(s): Alanyl-glutamine, Glutamine-S
• Empirical Formula (Hill Notation): C₈H₁₅N₃O₄
• CAS Number: 39537-23-0
• Molecular Weight: 217.22
• MDL number: MFCD00133046
• PubChem Substance ID: 24891211
• NACRES: NA.75

Properties

• product line: BioReagent
• Quality Level: 300
• Assay: ≥98% (HPLC)
• form: powder
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable
• color: white to off-white
• storage temp.: room temp
• SMILES string: NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
• InChI: 1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
• InChI key: HJCMDXDYPOUFDY-WHFBIAKZSA-N

Description

Application

Ala-Gln has been used:

• as a supplement in NeuralQ^™ medium
• as a component in growth medium and incubation medium (IM) for retinal cell lines
• for experimental treatment of retinal cell lines respectively

Biochem/physiol Actions

Alanyl-glutamine (Ala-Gln) is a dipeptide that is used as a substitute for glutamine in mammalian cell culture media, because of the instability of glutamine in solution and the formation of ammonia as a breakdown product of glutamine in solution, which can have deleterious effects on cells in culture. Ala-Glu is stable to heat sterilization and is less ammonia genic than glutamine, which contributes to its advantages as a media component. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.

Analysis Note

This product is cell culture tested (0.5 mg/ml) and insect cell culture tested (0.2 mg/ml). It is appropriate for use in cell culture and insect cell culture applications at 2-10 mM.

Legal Information

NeuralQ is a trademark of GlobalStem

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves