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ProteoMass ACTH Fragment 18-39 MALDI-MS Standard

vial of 10 nmol, monoisotopic mol wt 2,464.1989 Da

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Adrenocorticotropic hormone fragment 18-39
CAS Number:
MDL number:
PubChem Substance ID:

mol wt

monoisotopic mol wt 2,464.1989 Da

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vial of 10 nmol

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vial of 10 nmol




vial of 10 nmol


vial of 10 nmol

mol wt

monoisotopic mol wt 2,464.1989 Da

mol wt


mol wt

(M+H+) 16,952.27 Da by calculation

mol wt

monoisotopic mol wt 756.3997 Da

Amino Acid Sequence


General description

The single peptide or protein standard is used to calibrate and test matrix assisted laser desorption ionization (MALDI) mass spectrometers. Adrenocorticotropic hormone (ACTH) is synthesized from its precursor pro-opiomelanocortin (POMC). It is released from anterior pituitary gland in response to corticotropin-releasing hormone (CRH) from hypothalamus.


Peptide calibration standard for MALDI-MS instruments; 1 vial contains 10 nmols.
ProteoMass ACTH fragment 18-39 MALDI-MS standard has been used as a peptide calibration standard for matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry (MS) instruments.

Biochem/physiol Actions

Adrenocorticotropic hormone (ACTH) stimulates the synthesis and release of glucocorticoids and androgens through cAMP-dependent by a G-protein coupled receptor in adrenal gland. Overproduction of ACTH leads to marked skin pigmentation.

Storage and Stability

Each standard is stored at room temperature and is shipped at ambient temperature. Standard stock solutions can be frozen in aliquots, but should not be subjected to more than 3 freeze-thaw cycles. Standard solutions are recommended for use for no longer than one month after reconstitution.

Legal Information

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

related product

Product No.

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Salivary peptidome profiling for diagnosis of severe early childhood caries.
Sun X, et al.
Journal of Translational Medicine, 14(1), 240-240 (2016)
Patient Education: A Practical Approach (2001)
Endocrinology (2001)
Isolation and Identification of Proteins Secreted by Cells Cultured within Synthetic Hydrogel-Based Matrices.
Sawicki LA, et al.
ACS biomaterials science & engineering, 4(3), 836-845 (2018)
Simon Ekström et al.
Journal of mass spectrometry : JMS, 42(11), 1445-1452 (2007-10-26)
A polymer microfabricated proteomic sample preparation and MALDI MS sample presentation device, the integrated selective enrichment target (ISET), comprising an array of perforated nanovials is reported. Each perforated nanovial can be filled with selective extraction media (microbeads) for purification and


One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.

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