Merck
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M9500

Sigma-Aldrich

DL-Methionine

≥99%

Synonym(s):
(±)-2-Amino-4-(methylmercapto)butyric acid, DL-2-Amino-4-(methylthio)butanoic acid
Linear Formula:
CH3SCH2CH2CH(NH2)COOH
CAS Number:
Molecular Weight:
149.21
Beilstein:
636185
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Assay

≥99%

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white

mp

280 °C (dec.) (lit.)

solubility

H2O: soluble

application(s)

peptide synthesis

SMILES string

CSCCC(N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChI key

FFEARJCKVFRZRR-UHFFFAOYSA-N

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This Item
64340M2768M0950000
DL-Methionine ≥99%

Sigma-Aldrich

M9500

DL-Methionine

DL-Methionine ≥99.0% (NT)

Sigma-Aldrich

64340

DL-Methionine

DL-Methionine BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

Sigma-Aldrich

M2768

DL-Methionine

DL-Methionine European Pharmacopoeia (EP) Reference Standard

M0950000

DL-Methionine

form

powder

form

powder or crystals

form

powder

form

-

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

color

white

color

white

color

white

color

-

mp

280 °C (dec.) (lit.)

mp

280 °C (dec.) (lit.)

mp

280 °C (dec.) (lit.)

mp

280 °C (dec.) (lit.)

solubility

H2O: soluble

solubility

5 M HCl: 1 g/10 mL, clear, colorless to almost colorless

solubility

H2O: 50 mg/mL, clear, colorless

solubility

-

General description

DL-Methionine is an essential amino acid containing sulphur. Methionine consists of an asymmetric carbon and exists as D (dextrogyre) and L (levogyre) optical isomers. The L-methionine is considered as biologically active. The racemic mixture of D and L-isomers forms DL-methionine, which is the commercially available methionine.

Application

DL-Methionine has been used to study its effect on the growth and feed utilization of Nile tilapia. It has also been used as a part of standard diet in animal models.

Biochem/physiol Actions

DL-Methionine is an amino acid that has a role in the defence of oxidative stress.
Methionine offers protection against disorders related to hair, skin and nails. It elevates lecithin production in the liver and thereby reduces cholesterol level. It naturally serves as a heavy metal chelating agent, regulating ammonia concentration in the urine. This ameliorates bladder irritation. Methionine is also known to induce hair growth.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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DL-Methionine sulfone ≥99.0% (NT)

Sigma-Aldrich

64410

DL-Methionine sulfone

L-Methionine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Sigma-Aldrich

M5308

L-Methionine

L-Methionine United States Pharmacopeia (USP) Reference Standard

USP

1411504

L-Methionine

L-Methionine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1241

L-Methionine

DL-Methionine from Methional and Hydrogen Cyanide - Cost Analysis - Methionine E11A, 6-6 (2016)
Partial replacement of fishmeal and fish oil by algal meals in diets of red drum Sciaenops ocellatus
Perez-Velazquez M, et al.
Aquaculture (Amsterdam, Netherlands), 487, 41-50 (2018)
Gel growth and characterization of beta-DL-methionine
Ramachandran E and Natarajan S
Crystal Research and Technology, 41(4), 411-415 (2006)
Glucose homeostasis in mice is transglutaminase 2 independent
Iismaa SE, et al.
PLoS ONE, 8(5), e63346-e63346 (2013)
Dietary Crystalline DL-Methionine Supplementation of Oilseed Meal-Based Diets: Effects on Growth and Feed Utilization of Juvenile Nile Tilapia (Oreochromis niloticus L.)
Agbo NW, et al.
American Journal of Experimental Agriculture, 4(11), 1385-1396 (2014)

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