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P1504

Sigma-Aldrich

TWEEN® 40

viscous liquid

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Synonym(s):
Polyoxyethylenesorbitan monopalmitate
CAS Number:
MDL number:
NACRES:
NA.25

description

non-ionic

Quality Level

Assay

~90.0% (GC)

form

viscous liquid

mol wt

estimated mol wt 1277

composition

Palmitic acid, ~90% (balance primarily stearic acid)

technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

CMC

0.027 (20-25°C)

HLB

15.6

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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Sigma-Aldrich

P1504

TWEEN® 40

ECO TWEEN® 40 viscous liquid

STS0201

ECO TWEEN® 40

TWEEN® 20 for molecular biology, viscous liquid

P9416

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TWEEN® 20 Low-peroxide; Low-carbonyls

P6585

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assay

~90.0% (GC)

assay

~90.0% (GC)

assay

>40% (GC)

assay

-

form

viscous liquid

form

viscous liquid

form

viscous liquid

form

viscous liquid

mol wt

estimated mol wt 1277

mol wt

estimated mol wt 1277

mol wt

~1228

mol wt

~1228

description

non-ionic

description

non-ionic

description

non-ionic

description

non-ionic

CMC

0.027 (20-25°C)

CMC

0.027 (20-25°C)

CMC

60 mg/L

CMC

0.06 mM (20-25°C)

General description

Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, is a non-ionic detergent.

Application

Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid


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25G
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Determination of iodide in urine based on chemiluminescence system of cerium (IV)-tween 40-iodide
Li and Xie
Journal of Luminescence, 132, 5-5 (2012)
Christine Boesch-Saadatmandi et al.
Cytotechnology, 63(1), 89-97 (2010-12-15)
The present investigation aimed to compare fetal calf serum (FCS) and Tween 40 with the commonly employed tetrahydrofuran (THF) with respect to cytotoxicity, stability of the solubilized carotenoids, and uptake and accumulation of the xanthophylls astaxanthin (AX) and canthaxanthin (CX)
Sinead M O'Sullivan et al.
The British journal of nutrition, 91(5), 757-764 (2004-05-13)
Epidemiological evidence suggests that dietary intake of carotenoids and tocopherols may influence the risk of certain chronic diseases, such as cancer and CVD. In vitro studies investigating the synergistic effects of mixtures of carotenoids and tocopherols have been hindered due
Matija Tomsic et al.
International journal of pharmaceutics, 327(1-2), 170-177 (2006-08-26)
Small-angle X-ray scattering technique has been used to study the structural properties of the quaternary microemulsion Tween 40/Imwitor 308/isopropyl myristate/water and of five-component system obtained by the addition of the drug ketoprofen to the original quaternary system. The results enlighten
Branka Rozman et al.
Drug delivery, 14(4), 235-245 (2007-05-15)
An interesting strategy for protecting skin from excessive exposure to free radicals is to support the skin endogenous antioxidant system. As the balance between different skin antioxidants is very important, a combined therapy using at least two antioxidants is desirable.

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