P4333

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P4333

Penicillin-Streptomycin

Solution stabilized, with 10,000 units penicillin and 10 mg streptomycin/mL, 0.1 μm filtered, BioReagent, suitable for cell culture

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Synonym(s):

Pen-Strep

NACRES:

NA.76

Quality Level

300

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

concentration

100 ×

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes
protein synthesis | interferes

shipped in

dry ice

storage temp.

−20°C

SMILES string

CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(O)=O.CNC[C@H]4[C@H](O)[C@@H](O)[C@H](CCO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)C5(O)C=O)O[C@H]6[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]6NC(N)=N

InChI

1S/C23H43N7O12.C16H18N2O4S/c1-7-23(38,6-32)18(42-19-8(5-28-2)12(33)13(34)9(40-19)3-4-31)20(39-7)41-17-11(30-22(26)27)14(35)10(29-21(24)25)15(36)16(17)37;1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h6-20,28,31,33-38H,3-5H2,1-2H3,(H4,24,25,29)(H4,26,27,30);3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t7-,8-,9-,10+,11-,12-,13-,14+,15-,16+,17+,18-,19-,20-,23+;11-,12+,14-/m01/s1

InChI key

KMOOCZWLFBSQCW-XFOLRDBHSA-N

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This Item	P0781	P4458	11074440001
Sigma-Aldrich P4333 Penicillin-Streptomycin	Sigma-Aldrich P0781 Penicillin-Streptomycin	Sigma-Aldrich P4458 Penicillin-Streptomycin	Roche 11074440001 Penicillin-Streptomycin
sterility 0.1 μm filtered	sterility 0.1 μm filtered	sterility 0.1 μm filtered	sterility non-sterile; 0.2 μm filtered
product line BioReagent	product line BioReagent	product line BioReagent	product line -
form liquid	form liquid	form liquid	form lyophilized (clear, colorless solution after reconstitution)
concentration 100 ×	concentration 100 ×	concentration 50 ×	concentration 50 mg/mL streptomycin in 0.9% NaCl (as sulfate), 50,000 U/mL penicillin in 0.9% NaCl
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
impurities endotoxin, tested	impurities endotoxin, tested	impurities endotoxin, tested	impurities -

General description

Penicillin Streptomycin solution, also known as Pen Strep, is the most commonly used antibiotic solution for the culture of mammalian cells.Penicillin Streptomycin solution is used to maintain sterile conditions during cell culture, and they show few adverse effects on the cultured cells.

Application

Penicillin-Streptomycin is used to supplement cell culture media to control bacterial contamination. It is recommended for use in cell culture applications at 10 mL/L.
Penicillin streptomycin solution has been used as a supplement in different types of media, including RGC (retinal ganglion cells) culture, α-MEM (minimum essential medium) growth medium, Dulbecco′s modified Eagle′s medium (DMEM)/nutrient mixture F-12 Ham, DMEM and DMEM/F-12 + GlutaMax.

Components

This product is formulated to contain 10,000 units penicillin and 10 mg streptomycin/mL solubilized in a proprietary citrate buffer.

Other Notes

20ml,100ml

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Storage class (TRGS 510): Non Combustible Liquids

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)