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  • SML0595
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SML0595

Sigma-Aldrich

A-286982

≥95% (HPLC)

Synonym(s):
(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
Empirical Formula (Hill Notation):
C24H27N3O4S
CAS Number:
Molecular Weight:
453.55
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

−20°C

InChI

1S/C24H27N3O4S/c1-17(2)20-6-4-5-7-22(20)32-23-10-8-19(16-21(23)27(30)31)9-11-24(29)26-14-12-25(13-15-26)18(3)28/h4-11,16-17H,12-15H2,1-3H3/b11-9+

InChI key

HTGGAYLWTDOFDK-PKNBQFBNSA-N

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A 83-01 ≥98% (HPLC)

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assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

white to beige

color

white to tan

color

white to beige

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: >10 mg/mL

solubility

DMSO: 15 mg/mL, clear

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

2-8°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Biochem/physiol Actions

A-286982 blocks binding of lymphocyte function-associated antigen-1 (LFA-1) with the cell adhesion molecule ICAM-1. The IC50 in a cell based assay is 35 nM.

Other Notes

Air sensitive

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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