Merck
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SRP6182

Sigma-Aldrich

Human Serum Albumin

≥98% (SDS-PAGE)

Synonym(s):
GIG20, GIG42, HSA, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, serum albumin
NACRES:
NA.32

biological source

human

assay

≥98% (SDS-PAGE)

form

liquid

mol wt

66.4 kDa

packaging

pkg of 1 mg

concentration

10 mg/mL

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... ALBU(213)

General description

The gene HSA (human serum albumin) is mapped to human chromosome 4q13.3.[1] The gene encodes a protein of 585 amino acids with a molecular weight of 66.4kDa.[2] HSA is the most abundant protein in the plasma and has many metal-binding sites.[3][4]

Application

HSA (human serum albumin) has been used for the development of automated dye-binding method for serum albumin determination using bromcresol purple.[5] It has also been used to study effect of HSA on DNA transfection by lipoplexes.[6]

Biochem/physiol Actions

HSA (human serum albumin) mainly works as a carrier for various nutrients, metabolites and xenobiotics. It interacts with plasma zinc and regulates uptake of zinc in cells.[4] HSA plays a crucial role in drug pharmacokinetics.[3] It also controls oncotic pressure and volume of the blood.[7] Mutations in the gene are linked with congenital analbuminemia and familial dysalbuminemic hyperthyroxinemia.[1][8]

Physical form

Sterile filtered yellowish liquid.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

Certificate of Analysis

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Certificate of Origin

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