Merck
All Photos(4)

T0665

Sigma-Aldrich

holo-Transferrin human

powder, BioReagent, suitable for cell culture, ≥97%

Synonym(s):
Siderophilin, iron-saturated
CAS Number:
EC Number:
MDL number:
NACRES:
NA.75

biological source

human plasma

Quality Level

description

Iron-saturated

product line

BioReagent

assay

≥97%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

HIV and HBsAg, none detected
endotoxin, tested

solubility

H2O: 50 mg/mL

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

Gene Information

human ... TF(7018)

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Application

Transferrin is the primary iron binding and cell delivery molecule present in serum. Serum-free cell culture systems require a delivery format for iron. Transferrin is the preferential delivery form of iron because cells process transferrin bound iron in a physiologically appropriate way through transferrin receptors on the cell surface. Human holo-transferrin is a high affinity transferrin that can be used with a wide range of cells types. Human holo-transferrin is loaded with iron prior to use and can be added directly to iron poor or iron-free cell culture media.
holo-Transferrin human has been supplemented in Roswell Park Memorial Institute (RPMI) for proerythroblasts proliferation assay and also in culture media for inductively coupled plasma emission spectroscopy.

Packaging

50, 100, 500 mg in poly bottle
1 g in poly bottle

Biochem/physiol Actions

Provides iron to cells in a physiologically stable and safe form.

Preparation Note

Heat treated at 60 °C (minimum) for a minimum of 10 hours.

Analysis Note

Iron content by ICP reported on a lot-specific basis.
Purity by agarose gel electrophoresis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Not applicable

ISHL Notified Names

Not applicable

Certificate of Analysis

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Certificate of Origin

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SDS

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