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47858

Supelco

Thiamine Hydrochloride (B1)

analytical standard

Synonym(s):
Aneurine hydrochloride, Vitamin B1 hydrochloride, Thiamine hydrochloride
Empirical Formula (Hill Notation):
C12H17ClN4OS · HCl
CAS Number:
Molecular Weight:
337.27
Beilstein:
3851771
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

grade

analytical standard

CofA

current certificate can be downloaded

feature

standard type water soluble vitamin

packaging

ampule of 1000 mg

application(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

250 °C (dec.) (lit.)

Featured Industry

Pharmaceutical (small molecule)
Vitamins, Nutraceuticals, and Natural Products

format

neat

storage temp.

room temp

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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General description

Thiamine hydrochloride (B1) is a water soluble vitamin, which belongs the B-complex group of vitamins. It can exist both as a hemihydrate and as a nonstoichiometric hydrate. It can generally act like a co-enzyme for biochemical reactions involved in carbohydrate metabolism.

Application

Thiamine Hydrochloride (B1) may be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography (HPLC) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Wanamaker.PB and Massey K
Applied Pharmacology for Veterinary Technicians, (5) (2014)
Insights into the dehydration behavior of thiamine hydrochloride (Vitamin B1) hydrates: Part II
Chakravarty P, et al.
Journal of Pharmaceutical Sciences, 99(4), 1882-1895 (2010)
High-performance liquid chromatography method for the simultaneous determination of thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin in pharmaceutical formulations using coulometric electrochemical and ultraviolet detection
Marszall LM, et al.
Journal of Chromatography A, 1094(1-2), 91-98 (2005)
Josefin Engelhardt et al.
PloS one, 15(1), e0227201-e0227201 (2020-01-03)
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation...
Ashish K Singh et al.
Alcoholism, clinical and experimental research, 38(7), 2127-2137 (2014-06-17)
Chronic ethanol (EtOH) consumption is associated with oxidative tissue damage, decrease in antioxidant enzyme activities, and increase in hepatic and plasma lipids. This study investigates the effect of modified probiotic Escherichia coli Nissle 1917 (EcN) secreting pyrroloquinoline quinone (PQQ) against...

Articles

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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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