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PHR1232

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Kristina Riegel et al.
Clinical, cosmetic and investigational dermatology, 13, 499-510 (2020-08-18)
Clinical studies have confirmed that the hair-growth-promoting effect of approved oral drug combinations is beneficial for the treatment of diffuse telogen effluvium, which is characterized by the excessive loss of telogen club hairs. Since data elucidating the mode of action
Satoshi Yoshimoto et al.
International journal of molecular sciences, 21(2) (2020-01-19)
To investigate environmental factors that contribute to ultraviolet A (UVA)-induced oxidative stress, which accelerates the senescence and toxicity of skin cells, we irradiated human fibroblasts cultured in commonly used essential media with UVA and evaluated their viability and production of
Wenyan Kang et al.
Frontiers in cell and developmental biology, 7, 204-204 (2019-10-15)
Fusobacterium nucleatum (F. nucleatum) is a crucial periodontal pathogen and human gingival fibroblasts (GFs) are the first line of defense against oral pathogens. However, the research on potential molecular mechanisms of host defense and effective treatment of F. nucleatum infection
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C Basavanta Kumar et al.
Asian-Australasian journal of animal sciences, 29(11), 1616-1624 (2016-10-27)
The aim of present experiment was to investigate the effect of protein reduction in commercial broiler chicken rations with incorporation of de-oiled rice bran (DORB) and supplementation of limiting amino acids (valine, isoleucine, and/or tryptophan) with ration formulation either on
Rafael Longhi et al.
European journal of nutrition, 56(3), 1003-1016 (2016-01-13)
Recent data regarding trans fatty acids (TFAs) have implicated these lipids as particularly deleterious to human health, causing systemic inflammation, endothelial dysfunction and possibly inflammation in the central nervous system (CNS). We aimed to clarify the impact of partially hydrogenated
Joost Schalkwijk et al.
Science translational medicine, 11(510) (2019-09-20)
Malaria eradication is critically dependent on new therapeutics that target resistant Plasmodium parasites and block transmission of the disease. Here, we report that pantothenamide bioisosteres were active against blood-stage Plasmodium falciparum parasites and also blocked transmission of sexual stages to
My Tuyen Thi Nguyen et al.
Nutrients, 12(6) (2020-06-21)
Vitamins are the essential elements for human life and, particularly, for infant health. Human milk is the best source of nutrients for newborns, however, the information of vitamins in Asian maternal milk is still limited. In this study, we have
Žane Temova Rakuša et al.
Food chemistry, 337, 127768-127768 (2020-09-06)
A stability-indicating HPLC-DAD method for simultaneous determination of all nine main water-soluble vitamins, in addition to two commonly used vitamers, was developed and fully validated in analytical ranges, adjusted to their recommended dietary allowance values. An XSelect CSH C18 column
Chunwu Zhu et al.
Science advances, 4(5), eaaq1012-eaaq1012 (2018-05-29)
Declines of protein and minerals essential for humans, including iron and zinc, have been reported for crops in response to rising atmospheric carbon dioxide concentration, [CO2]. For the current century, estimates of the potential human health impact of these declines
Rafael Longhi et al.
European journal of nutrition, 57(5), 1913-1924 (2017-06-02)
Previously showed that dietary trans fatty acids (TFAs) may cause systemic inflammation and affect the central nervous system (CNS) in Wistar rats by increased levels of cytokines in the cerebrospinal fluid (CSF) and serum (Longhi et al. Eur J Nutr
E Baéza et al.
British poultry science, 62(2), 261-269 (2020-10-29)
1. The aim of the present study was to investigate increasing amount of n-3 fatty acids (FA) in common edible chicken meat cuts by testing different levels of extruded linseeds (LS) and rapeseed oil in growing and finishing diets. Another
Max Michel et al.
Autophagy, 11(12), 2300-2308 (2015-08-04)
ATG101 is an essential component of the ULK complex responsible for initiating cellular autophagy in mammalian cells; its 3-dimensional structure and molecular function, however, are currently unclear. Here we present the X-ray structure of human ATG101. The protein displays an
Mark A A Harrison et al.
Cells, 10(1) (2020-12-31)
Macrophages and microglia represent the primary phagocytes and first line of defense in the peripheral and central immune systems. They activate and polarize into a spectrum of pro- and anti-inflammatory phenotypes in response to various stimuli. This activation is tightly
K Maráková et al.
Die Pharmazie, 69(9), 663-668 (2014-10-03)
The advanced hyphenated method based on capillary electrophoresis (CE) on-line combined with electrospray ionization (ESI) and tandem mass spectrometry (MS/MS, here triple quadrupole, QqQ) was developed and applied in pharmaceutical analysis in this work. Under the optimized CE separation (background
Dietary supplements containing vitamins and minerals: Formulation, optimization and evaluation
Rajakumari R, et al.
Powder Technology, 336, 481-492 (2018)
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