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Andrew L Garfoot et al.
Infection and immunity, 82(1), 393-404 (2013-11-06)
During infection of the mammalian host, Histoplasma capsulatum yeasts survive and reside within macrophages of the immune system. Whereas some intracellular pathogens escape into the host cytosol, Histoplasma yeasts remain within the macrophage phagosome. This intracellular Histoplasma-containing compartment imposes nutritional
Alexandra C Weaver et al.
Toxins, 6(12), 3336-3353 (2014-12-24)
To evaluate the effects of the mycotoxins deoxynivalenol (DON) and zearalenone (ZEA) on pigs and the benefits of two mycotoxin mitigation strategies, gilts (n = 84, 9.1 ± 0.1 kg) were allotted to four treatments: CON (control); MT (4.8 mg/kg
Author reply: To PMID 24576886.
Dalia G Said et al.
Ophthalmology, 121(12), e68-e68 (2014-08-12)
Immediate effect of ultraviolet-a collagen cross-linking therapy on the biomechanics and histology of the human cornea.
María A Del Buey et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 31(1), 70-71 (2015-01-20)
Arundhati Biswas et al.
PloS one, 8(3), e58190-e58190 (2013-03-14)
Two potential orthologs of the human riboflavin transporter 3 (hRFVT3) were identified in the C. elegans genome, Y47D7A.16 and Y47D7A.14, which share 33.7 and 30.5% identity, respectively, with hRFVT3. The genes are tandemly arranged, and we assign them the names
Jianmin Chen et al.
Drug development and industrial pharmacy, 41(3), 415-422 (2014-01-01)
Coated microneedles have been paid much attention recently, and several coating strategies have been developed to address the problems during coating process. However, there are still some unresolved issues, such as, precise control requirements, microneedle substrate contamination and high processing
Bárbara J Henriques et al.
Current medicinal chemistry, 17(32), 3842-3854 (2010-09-23)
Riboflavin, commonly known as vitamin B2, is the precursor of flavin cofactors. It is present in our typical diet, and inside the cells it is metabolized to FMN and FAD. As a result of their rather unique and flexible chemical
David Tabibian et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(12), 855-857 (2014-12-02)
To report the use of accelerated photoactivated chromophore for keratitis-corneal collagen cross-linking (PACK-CXL) as a first-line treatment in a patient with an atypical fungal keratitis. Case report and literature review. A patient who presented with a painful peripheral corneal infiltrate
Chibuzo C Odigwe et al.
The Cochrane database of systematic reviews, (4)(4), CD008147-CD008147 (2010-04-16)
Protein Energy Malnutrition is an important cause of child morbidity and mortality in middle- and low-income countries. It has been suggested that excessive free radical activity may be responsible for the clinical manifestation of kwashiorkor. Antioxidants may be able to
High fluence iontophoretic corneal collagen cross-linking: in vivo OCT imaging of riboflavin penetration.
Paolo Vinciguerra et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(6), 376-377 (2013-06-07)
Nacim Bouheraoua et al.
Investigative ophthalmology & visual science, 55(11), 7601-7609 (2014-10-30)
We compared the efficacy and early morphological changes in the cornea following conventional (C-CXL), transepithelial by iontophoresis (I-CXL), and accelerated (A-CXL) collagen cross-linking in keratoconus. A total of 45 eyes of 45 patients with progressive keratoconus who underwent corneal collagen
Hiroki Yoshimatsu et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(2), G102-G110 (2013-11-23)
Riboflavin, also known as vitamin B2, is transported across the biological membrane into various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small intestine and has been suggested to localize in the apical membranes of the intestinal
Simultaneous determination of niacinamide, pyridoxine, riboflavin, and thiamine in multivitamin products by high-pressure liquid chromatography
Walker MC, et al.
Journal of Pharmaceutical Sciences, 70(1), 99-101 (1981)
Jian-Zhuang Tan et al.
Journal of the science of food and agriculture, 95(1), 126-135 (2014-04-15)
The effects of dietary l-arginine (Arg) on immunosuppression following infectious bursal disease virus (IBDV) inoculation in broiler chickens were evaluated. The design of this study was a 5 × 2 factorial arrangement (n = 5) with five Arg concentrations (starter:
Paula Dominguez-Salas et al.
The American journal of clinical nutrition, 97(6), 1217-1227 (2013-04-12)
Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In humans, altered DNA methylation patterns have been observed in offspring whose mothers were
Jose L Güell et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(4), 286-288 (2014-04-08)
To present a case of a late, deep stromal scar in a 22-year-old patient with forme fruste keratoconus who underwent combined corneal cross-linking and photorefractive keratectomy (PRK). Topography-guided corneal cross-linking combined with corneal PRK (without complications) was performed in both
Mattias Johansson et al.
Journal of the National Cancer Institute, 106(12), doi:10-doi:10 (2014-11-08)
The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants
Inong R Gunanti et al.
The Journal of nutrition, 144(12), 2027-2033 (2014-11-21)
Micronutrient status may be a contributing factor to the development of childhood obesity in many industrializing countries passing the nutritional transition. The few studies investigating associations between serum concentrations of vitamin B and intake of B vitamins with adiposity, however
Stella Vitt et al.
Journal of molecular biology, 426(15), 2813-2826 (2014-06-03)
The reversible redox reaction between coenzyme F420 and H2 to F420H2 is catalyzed by an F420-reducing [NiFe]-hydrogenase (FrhABG), which is an enzyme of the energy metabolism of methanogenic archaea. FrhABG is a group 3 [NiFe]-hydrogenase with a dodecameric quaternary structure
Ali Fadlallah et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(10), 688-693 (2014-10-08)
To evaluate the safety and clinical outcome of combined non-topography-guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) for the treatment of mild refractive errors in patients with early stage keratoconus. A retrospective, nonrandomized study of patients with early stage
Ithar M Beshtawi et al.
Journal of cataract and refractive surgery, 39(3), 451-462 (2013-03-20)
Photodynamic collagen crosslinking (CXL) using ultraviolet-A (UVA) irradiation combined with the photosensitizer riboflavin has been introduced as a new treatment for progressive keratoconus. The results of clinical studies are promising, but the efficacy of the treatment in halting the progression
Maria De Angelis et al.
PloS one, 9(9), e107232-e107232 (2014-09-30)
Lactobacillus rossiae is an obligately hetero-fermentative lactic acid bacterium, which can be isolated from a broad range of environments including sourdoughs, vegetables, fermented meat and flour, as well as the gastrointestinal tract of both humans and animals. In order to
Simultaneous determination of riboflavin phosphate and other ingredients in a multivitamin pharmaceutical preparation by on-line automated LC coupled with pre-column immobilized enzyme reactor
Ono M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(1-2), 325-334 (2002)
Djamila Achouri et al.
Drug development and industrial pharmacy, 41(3), 493-501 (2014-02-14)
In the field of keratoconus treatment, a lipid-based liquid crystal nanoparticles system has been developed to improve the preocular retention and ocular bioavailability of riboflavin, a water-soluble drug. The formulation of this ophthalmic drug delivery system was optimized by a
Arthur Hammer et al.
Investigative ophthalmology & visual science, 55(5), 2881-2884 (2014-03-29)
New corneal cross-linking (CXL) devices are capable of using higher UV-A light irradiances than used in original CXL protocols. The Bunsen-Roscoe law states that a photochemical reaction should stay constant if the delivered total energy is kept constant; however, little
Maria Gkika et al.
International ophthalmology, 31(4), 309-319 (2011-08-19)
Corneal collagen cross-linking (CXL) using riboflavin and ultraviolet-A irradiation is a common method of tissue stabilization and has been developed primarily to address the need of treating keratoconus. CXL's promising results on keratoconus indicated that it might be effective in
Xuan Chi et al.
Transfusion, 54(1), 74-85 (2013-05-10)
Pathogen reduction technologies (PRTs) can induce platelet (PLT) lesions that reduce PLT survival and recovery from circulation and may be associated with acute lung injury (ALI). Human PLTs (hPLTs) in plasma with or without single or multiple Mirasol PRT treatments
Ryan A Kelley et al.
The Journal of biological chemistry, 290(8), 5041-5052 (2014-12-30)
Retbindin is a novel retina-specific protein of unknown function. In this study, we have used various approaches to evaluate protein expression, localization, biochemical properties, and function. We find that retbindin is secreted by the rod photoreceptors into the inter-photoreceptor matrix
Caterina Garone et al.
JAMA neurology, 70(9), 1177-1179 (2013-07-10)
Mendelian forms of complex I deficiency are usually associated with fatal infantile encephalomyopathy. Application of "MitoExome" sequencing (deep sequencing of the entire mitochondrial genome and the coding exons of >1000 nuclear genes encoding the mitochondrial proteome) allowed us to reveal
Damon H May et al.
The British journal of nutrition, 110(10), 1760-1770 (2013-05-10)
Metabolomic profiles were used to characterise the effects of consuming a high-phytochemical diet compared with a diet devoid of fruits and vegetables (F&V) in a randomised trial and cross-sectional study. In the trial, 8 h fasting urine from healthy men
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