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  • Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(II), nickel(II), cobalt(II) and zinc(II): structural features, biological evaluation and perspectives.

Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(II), nickel(II), cobalt(II) and zinc(II): structural features, biological evaluation and perspectives.

Dalton transactions (Cambridge, England : 2003) (2013-03-27)
George Psomas, Dimitris P Kessissoglou
ABSTRACT

The structural features of copper(II), nickel(II), cobalt(II) and zinc(II) complexes with the antimicrobial drugs quinolones and non-steroidal anti-inflammatory drugs (NSAIDs) as ligands are discussed. The binding properties of these complexes to biomolecules (calf-thymus DNA, bovine or human serum albumin) are presented and evaluated. The biological activity (antimicrobial, antioxidant and antiproliferative) of selected complexes is investigated. Further perspectives concerning the synthesis and the biological activity of novel complexes with quinolones or NSAIDs attractive to synthetic chemists, biochemists and/or biologists are presented.

MATERIALS
Product Number
Brand
Product Description

Nickel, foil, 2m coil, thickness 0.0125mm, annealed, 99%
Nickel, foil, 8mm disks, thickness 0.025mm, as rolled, 100%
Nickel, foil, 6mm disks, thickness 0.05mm, as rolled, 99.98%
Nickel, foil, light tested, 100x100mm, thickness 0.05mm, annealed, 99%
Nickel, foil, light tested, 100x100mm, thickness 0.05mm, as rolled, 100%
Nickel, foil, 8mm disks, thickness 0.05mm, as rolled, 99.99+%
Nickel, foil, 8mm disks, thickness 0.008mm, 99.95%
Nickel, foil, 150x150mm, thickness 0.125mm, as rolled, 99.99+%
Nickel, foil, light tested, 25x25mm, thickness 0.05mm, annealed, 99%
Nickel, foil, light tested, 25x25mm, thickness 0.03mm, 99.9%
Nickel, foil, light tested, 200x200mm, thickness 0.05mm, as rolled, 99.98%
Nickel, foil, 6mm disks, thickness 0.125mm, as rolled, 100%
Nickel, foil, not light tested, 100x100mm, thickness 0.007mm, 99.95%
Nickel, foil, 8mm disks, thickness 0.005mm, as rolled, 99.9%
Nickel, foil, 2m coil, thickness 0.0075mm, 99.9%
Nickel, foil, light tested, 100x100mm, thickness 0.075mm, as rolled, 99.98%
Nickel, foil, 8mm disks, thickness 0.125mm, as rolled, 99.99+%
Nickel, foil, 6mm disks, thickness 0.50mm, annealed, 99%
Nickel, foil, 6mm disks, thickness 0.05mm, as rolled, 100%
Nickel, foil, 100x100mm, thickness 0.25mm, as rolled, 99.999%
Nickel, foil, light tested, 25x25mm, thickness 0.015mm, 99.9%
Nickel, foil, not light tested, 300x300mm, thickness 0.0075mm, 99.9%
Nickel, foil, 25mm disks, thickness 0.20mm, annealed, 99%
Nickel, foil, not light tested, 148x150mm, thickness 0.0075mm, 99.95%
Nickel, microfoil, disks, 10mm, thinness 0.1μm, specific density 93.4μg/cm2, permanent mylar 3.5μm support, 99.99+%
Nickel, foil, 25mm disks, thickness 0.5mm, as rolled, 99.99+%
Nickel, foil, not light tested, 100x100mm, thickness 0.009mm, 99.95%
Nickel, pellets, 100g, max. size 15mm, 99.99+%
Nickel, foil, 50x50mm, thickness 1.6mm, 99%
Nickel, foil, light tested, 25x25mm, thickness 0.008mm, 99.95%