ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
別名:
ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1
Species:
Human ABCA4 (24), Mouse Abca4 (11304), Rat Abca4 (310836), chicken ABCA4 (424490), Horse ABCA4 (100058746), dog ABCA4 (444852), domestic cat ABCA4 (101099571), Thale Cress ABCA4 (823929), naked mole-rat Abca4 (101725111), domestic guinea pig Abca4 (100725431) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(24) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]
- Mouse(11304) ATP-binding cassette, sub-family A (ABC1), member 4
- Rat(310836) ATP-binding cassette, subfamily A (ABC1), member 4
- chicken(424490) ATP-binding cassette, sub-family A (ABC1), member 4
- Horse(100058746) ATP-binding cassette, sub-family A (ABC1), member 4
- dog(444852) ATP-binding cassette, sub-family A (ABC1), member 4
- domestic cat(101099571) ATP-binding cassette, sub-family A (ABC1), member 4
- Thale Cress(823929) ATP binding cassette subfamily A4
- naked mole-rat(101725111) ATP-binding cassette, sub-family A (ABC1), member 4
- domestic guinea pig(100725431) ATP-binding cassette, sub-family A (ABC1), member 4
- sheep(101107561) ATP-binding cassette, sub-family A (ABC1), member 4
- cow(281584) ATP-binding cassette, sub-family A (ABC1), member 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-ABCA4 Antibody, clone 5B4, clone 5B4, from mouse,
交差性
bovine, human, mouse
アプリケーション
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ABCA4 Antibody, clone 3F4, clone 3F4, from mouse,
交差性
bovine, human
アプリケーション
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-ABCA4 Antibody, clone TMR1, clone TMR1, from mouse,
交差性
bovine, human, mouse
アプリケーション
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-ABCA4 Antibody, clone 5D7.1, clone 5D7.1, from mouse,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
Anti-ABCA4, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
esiRNA
製品番号
詳細
Species