ATM
ataxia telangiectasia mutated
別名:
AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
Species:
Human ATM (472), Mouse Atm (11920), Rat Atm (300711), Thale Cress ATM (823975), Zebrafish atm (403064), chicken ATM (395401), dog ATM (479450), domestic cat ATM (101089291), Horse ATM (100061765), cow ATM (526824) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(472) Summary: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
- Mouse(11920) ataxia telangiectasia mutated homolog (human)
- Rat(300711) ataxia telangiectasia mutated
- Thale Cress(823975) serine/threonine-protein kinase ATM
- Zebrafish(403064) ataxia telangiectasia mutated
- chicken(395401) ataxia telangiectasia mutated
- dog(479450) ataxia telangiectasia mutated
- domestic cat(101089291) ataxia telangiectasia mutated
- Horse(100061765) ataxia telangiectasia mutated
- cow(526824) ataxia telangiectasia mutated
- sheep(101105847) ataxia telangiectasia mutated
- domestic guinea pig(100717983) ataxia telangiectasia mutated
- naked mole-rat(101718948) ataxia telangiectasia mutated
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗リン酸化ATM（Ser1981）抗体 クローン10H11.E12, clone 10H11.E12, Upstate®, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-ATM phosphoSer1981 Antibody, clone 10H11.E12, clone 10H11.E12, Chemicon®, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate, clone 10H11.E12, from mouse, PE,
交差性
human, mouse, rat
アプリケーション
flow cytometry
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12, Ascites Free, clone 10H11.E12, from mouse,
交差性
human, mouse
アプリケーション
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Proteins
製品番号
詳細
Species