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Merck

BAD

BCL2-associated agonist of cell death

別名:
BBC2, BCL2L8
Species:
UniProtKB ID:
遺伝子ID:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

Custom & Knockdown Gene Products

Small Molecule - Antagonist

製品番号
詳細
Species
2,3-ジヒドロキシナフタレン, ≥98.0% (HPLC),
Species
human
4-ビフェニル酢酸, 98%,
Species
human
ビフェニル-4-カルボン酸, 95%,
Species
human
(±)-ゴシポール 綿実由来, ≥95% (HPLC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
交差性
bovine, canine, human, mouse, rat
アプリケーション
immunoprecipitation (IP)
inhibition assay

western blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
交差性
human
アプリケーション
western blot
Anti-Phospho-Bad (Ser99) Antibody, from rabbit,
交差性
human
アプリケーション
western blot
Anti-Phospho-Bad-S155 antibody produced in rabbit, ,
交差性
human
アプリケーション
western blot

Proteins

製品番号
詳細
Species
BAD、GSTタグ融合 ヒト, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human BAD,
Species
human