BIN1
bridging integrator 1
別名:
AMPH2, AMPHL, SH3P9
Species:
Human BIN1 (274), Mouse Bin1 (30948), Rat Bin1 (117028), Zebrafish bin1 (447863), chicken BIN1 (424228), domestic guinea pig Bin1 (100722858), dog BIN1 (483870), sheep BIN1 (101119119), naked mole-rat Bin1 (101723039), fruit fly Bin1 (41965) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(274) Summary: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011]
- Mouse(30948) bridging integrator 1
- Rat(117028) bridging integrator 1
- Zebrafish(447863) bridging integrator 1
- chicken(424228) bridging integrator 1
- domestic guinea pig(100722858) bridging integrator 1
- dog(483870) bridging integrator 1
- sheep(101119119) bridging integrator 1
- naked mole-rat(101723039) bridging integrator 1
- fruit fly(41965) Bicoid interacting protein 1
- domestic cat(101097908) bridging integrator 1
- Horse(100052213) bridging integrator 1
- cow(614576) bridging integrator 1
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗BIN1抗体 ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗BIN1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
抗BIN1抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
western blot
Anti-Bin1 Antibody, clone 99D, clone 99D, Upstate®, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Bin1, clone 99D (Ascites Free) Antibody, clone 99D, 1 mg/mL, from mouse,
交差性
chicken, human, mouse
アプリケーション
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot