コンテンツへスキップ
Merck

C4A

complement component 4A (Rodgers blood group)

別名:
C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG
Species:
UniProtKB ID:
遺伝子ID:
  • Human(720) Summary: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(625018) complement component 4A (Rodgers blood group)
  • Rat(24233) complement component 4A (Rodgers blood group)
  • Horse(100059239) complement component 4A (Rodgers blood group)
  • dog(481722) complement component 4A (Rodgers blood group)
  • naked mole-rat(101719002) complement component 4A (Rodgers blood group)
  • domestic guinea pig(100728345) complement component 4A (Rodgers blood group)
  • Domestic Rabbit(100356976) complement component 4A (Rodgers blood group)
  • sheep(101123672) complement component 4A (Rodgers blood group)
  • cow(280678) complement component 4A

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
抗C4A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-Complement C4A Antibody, clone 4C3F2, Rabbit Monoclonal, ,
交差性
human
アプリケーション
immunofluorescence
western blot
抗C4A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗C4A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry

Proteins

製品番号
詳細
Species
補体C4 ヒト血清由来, ≥300,000 C4H50 units/mg protein,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse C4a (2),
Species
mouse
MISSION® esiRNA, targeting mouse C4a (1),
Species
mouse