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Merck

CASP10

caspase 10, apoptosis-related cysteine peptidase

別名:
ALPS2, FLICE2, MCH4
Species:
UniProtKB ID:
遺伝子ID:
  • Human(843) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • cow(100848685) caspase 10, apoptosis-related cysteine peptidase
  • chicken(424081) caspase 10, apoptosis-related cysteine peptidase
  • domestic cat(101085995) caspase 10, apoptosis-related cysteine peptidase
  • naked mole-rat(101712620) caspase 10, apoptosis-related cysteine peptidase
  • domestic guinea pig(100717714) caspase 10, apoptosis-related cysteine peptidase
  • Horse(100068201) caspase 10, apoptosis-related cysteine peptidase
  • dog(488472) caspase 10, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CASP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-CASP10 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
western blot
Anti-Caspase-10 Antibody, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
western blot
Anti Caspase 10 Antibody, clone 23GB3330, Rabbit Monoclonal, clone 23GB3330, recombinant rabbit monoclonal, expressed in HEK293 cells,
交差性
human
アプリケーション
flow cytometry
immunofluorescence

western blot
Monoclonal Anti-CASP10 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
proximity ligation assay

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CASP10,
Species
human