CCND1
cyclin D1
別名:
BCL1, D11S287E, PRAD1, U21B31
Species:
Human CCND1 (595), Mouse Ccnd1 (12443), Rat Ccnd1 (58919), sheep CCND1 (100144763), Domestic Rabbit CCND1 (100009036), Zebrafish ccnd1 (30222), dog CCND1 (449028), cow CCND1 (524530), domestic guinea pig Ccnd1 (100729808), chicken CCND1 (396341) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(595) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]
- Mouse(12443) cyclin D1
- Rat(58919) cyclin D1
- sheep(100144763) cyclin D1
- Domestic Rabbit(100009036) cyclin D1
- Zebrafish(30222) cyclin D1
- dog(449028) cyclin D1
- cow(524530) cyclin D1
- domestic guinea pig(100729808) cyclin D1
- chicken(396341) cyclin D1
- domestic cat(100037407) cyclin D1
- naked mole-rat(101712621) cyclin D1
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-Cyclin D Antibody, from rabbit, purified by affinity chromatography,
交差性
human, mouse, primate
アプリケーション
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
抗サイクリンD1抗体 クローン1J9 ZooMAb®ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CYCLIN D1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
western blot
Anti-Cyclin D1/2 Antibody, clone 5D4, clone 5D4, Upstate®, from mouse,
交差性
hamster, human, mouse, rat
アプリケーション
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-Cyclin D1 antibody produced in mouse, clone DCS-6,
交差性
human, mouse, nonhuman primates, rat
アプリケーション
flow cytometry
Proteins
製品番号
詳細
Species
CDK4/Cyclin D1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human
CDK4/サイクリンD1、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
CDK6/サイクリンD1, 活性型, His/GSTタグ付加 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human