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Merck

CCNH

cyclin H

別名:
CAK, p34, p37
Species:
UniProtKB ID:
遺伝子ID:
  • Human(902) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
  • Mouse(66671) cyclin H
  • Rat(84389) cyclin H
  • naked mole-rat(101714118) cyclin H
  • domestic guinea pig(100726162) cyclin H
  • sheep(101104905) cyclin H
  • chicken(427328) cyclin H
  • domestic cat(101095398) cyclin H
  • cow(615512) cyclin H
  • dog(479156) cyclin H
  • Zebrafish(541325) cyclin H
  • Horse(100065185) cyclin H

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-phospho-Cyclin H (pThr315) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
抗CCNH抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-Cyclin H Antibody, clone 3N5S3, Rabbit Monoclonal, ,
交差性
mouse
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗CCNH抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CCNH,
Species
human
MISSION® esiRNA, targeting mouse Ccnh,
Species
mouse