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Merck

CD46

CD46 molecule, complement regulatory protein

別名:
AHUS2, MCP, MIC10, TLX, TRA2.10
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4179) Summary: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
  • Mouse(17221) CD46 antigen, complement regulatory protein
  • Rat(29333) CD46 molecule, complement regulatory protein
  • cow(616002) CD46 molecule, complement regulatory protein
  • cow(280851) CD46 molecule, complement regulatory protein
  • domestic cat(101094152) CD46 molecule, complement regulatory protein
  • naked mole-rat(101704640) CD46 molecule, complement regulatory protein
  • domestic guinea pig(100135498) CD46 antigen, complement regulatory protein
  • dog(609365) CD46 molecule, complement regulatory protein

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Human CD46 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CD46 Antibody, clone TRA-2-10, clone TRA-2-10, from mouse,
交差性
human
アプリケーション
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

inhibition assay
Anti-CD46 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-CD46 Antibody, clone 8A9.1, clone 8A9.1, from mouse,
交差性
human
アプリケーション
flow cytometry
immunocytochemistry

western blot
Monoclonal Anti-CD46-PE antibody produced in mouse, clone MEM-258, purified immunoglobulin, buffered aqueous solution,
交差性
bovine, human
アプリケーション
flow cytometry
Monoclonal Anti-CD46-APC antibody produced in mouse, clone MEM-258, purified immunoglobulin, buffered aqueous solution,
交差性
bovine, human
アプリケーション
flow cytometry

Proteins

製品番号
詳細
Species
Monkey CD46-BC, His-Tag, recombinant, expressed in HEK 293 cells,
Species
mouse
Human CD46-BC, His-Tag, recombinant, expressed in HEK 293 cells,
Species
human
Human CD46-C, His-Tag, recombinant, expressed in HEK 293 cells,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CD46,
Species
human