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Merck

CDC27

cell division cycle 27

別名:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(217232) cell division cycle 27
  • Rat(360643) cell division cycle 27
  • naked mole-rat(101717421) cell division cycle 27
  • domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
  • fruit fly(38798) CG8610 gene product from transcript CG8610-RB
  • dog(490924) cell division cycle 27 homolog (S. cerevisiae)
  • chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
  • cow(540660) cell division cycle 27 homolog (S. cerevisiae)
  • domestic guinea pig(100731091) cell division cycle 27
  • Zebrafish(30450) cell division cycle 27
  • Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
  • sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-CDC27 Antibody, clone 7U5A3, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
western blot
モノクローナル抗Cdc27抗体 マウス宿主抗体, clone AF3.1, purified from hybridoma cell culture,
交差性
xenopus, bovine, canine, human, mouse, rat
アプリケーション
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

microarray

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CDC27,
Species
human
MISSION® esiRNA, targeting mouse Cdc27,
Species
mouse