コンテンツへスキップ
Merck

CHRM2

cholinergic receptor, muscarinic 2

別名:
HM2
Species:
Human CHRM2 (1129), Mouse Chrm2 (243764), Rat Chrm2 (81645), Domestic Rabbit CHRM2 (100342878), naked mole-rat Chrm2 (101714286), chicken CHRM2 (418126), domestic guinea pig Chrm2 (100715343), dog CHRM2 (403858), cow CHRM2 (522170), domestic cat CHRM2 (101099790) ...詳細
UniProtKB ID:
P08172, Q4VBK6, Q9P1X9
遺伝子ID:
  • Human(1129) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(243764) cholinergic receptor, muscarinic 2, cardiac
  • Rat(81645) cholinergic receptor, muscarinic 2
  • Domestic Rabbit(100342878) cholinergic receptor, muscarinic 2
  • naked mole-rat(101714286) cholinergic receptor, muscarinic 2
  • chicken(418126) cholinergic receptor, muscarinic 2
  • domestic guinea pig(100715343) cholinergic receptor, muscarinic 2
  • dog(403858) cholinergic receptor, muscarinic 2
  • cow(522170) cholinergic receptor, muscarinic 2
  • domestic cat(101099790) cholinergic receptor, muscarinic 2
  • sheep(101102897) cholinergic receptor, muscarinic 2
  • sheep(100628317) cholinergic receptor, muscarinic 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

製品番号
詳細
Species
P6503
ピロカルピン 塩酸塩, ≥99% (titration), powder,
Species
human
A2251
アセチル-β-メチルコリン クロリド, ≥98% (TLC), powder,
Species
human
P6628
ピロカルピン 硝酸塩, ≥98% (HPLC),
Species
human
O100
オキソトレモリンM, solid,
Species
human
M104
(±)-ムスカリン クロリド 水和物, ≥98% (HPLC),
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
M105
メトクトラミン 水和物, ≥97% (NMR), solid,
Species
human
SML1102
ダリフェナシン 臭化水素酸塩, ≥98% (HPLC),
Species
human
1485103
オキシブチニンクロリド, United States Pharmacopeia (USP) Reference Standard,
Species
human
O0288000
オキシブチニンクロリド, European Pharmacopoeia (EP) Reference Standard,
Species
human
1164200
ダリフェナシン 臭化水素酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
MAB367
抗ムスカリン性アセチルコリン受容体m2抗体、クローンM2-2-B3, clone M2-2-B3, Chemicon®, from rat,
交差性
human, mammals, monkey, rat
アプリケーション
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
WH0001129M1
Monoclonal Anti-CHRM2 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
SAB5702535
Anti-Muscarinic AChR M2 (ACM2) Antibody, clone 3T5W8, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
P127
(+)-ペンタゾシン, solid,
Species
rat, human
A8404
アミトリプチリン 塩酸塩, ≥98% (TLC), powder,
Species
human
D4526
ドキセピン 塩酸塩, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Species
human
H1512
ハロペリドール, powder,
Species
human, rat
51330
ハルマリン, ≥95%,
Species
human, rat

Small Molecule - Ligand

製品番号
詳細
Species
A138
アミノベンズトロピン, solid,
Species
human

Proteins

製品番号
詳細
Species
HTS115M
ChemiSCREEN Membrane Preparation Recombinant Human M2 Muscarinic Acetylcholine Receptor, Human M2 GPCR membrane prepation for Radioligand binding Assays.,
Species
human

esiRNA

製品番号
詳細
Species
EHU120771
MISSION® esiRNA, targeting human CHRM2,
Species
human