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Merck

CHRM4

cholinergic receptor, muscarinic 4

別名:
HM4, M4R
Species:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), domestic guinea pig Chrm4 (100714736), naked mole-rat Chrm4 (101726411), Domestic Rabbit CHRM4 (100008791), dog CHRM4 (611314), cow CHRM4 (512928), sheep CHRM4 (101114554), domestic cat CHRM4 (101088360)
UniProtKB ID:
P08173, B2RPP4, Q0VD60, Q4VBK7
遺伝子ID:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

製品番号
詳細
Species
P6503
ピロカルピン 塩酸塩, ≥99% (titration), powder,
Species
human
A2251
アセチル-β-メチルコリン クロリド, ≥98% (TLC), powder,
Species
human
P6628
ピロカルピン 硝酸塩, ≥98% (HPLC),
Species
human
O100
オキソトレモリンM, solid,
Species
human
M104
(±)-ムスカリン クロリド 水和物, ≥98% (HPLC),
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
B1390
ビサコジル, analytical standard, for drug analysis,
Species
human
T9778
トロピカミド, solid,
Species
human
S1875
(−)-スコポラミン 臭化水素酸塩 三水和物, >95% (HPLC), powder,
Species
human
A0257
アトロピン 硫酸塩 一水和物, ≥97% (TLC), crystalline,
Species
human
S8502
(−)-スコポラミンメチルブロミド, ≥98% (HPLC), powder,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
SAB4300824
Anti-CHRM4 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot
ZMS1165
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
ELISA
affinity binding assay
immunocytochemistry
western blot
MAB1578
抗ムスカリン性アセチルコリン受容体m4抗体 クローン18C7.2, clone 18C7.2, Chemicon®, from mouse,
交差性
monkey
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
western blot
MAB1576
抗ムスカリン性アセチルコリン受容体m4抗体、クローン17F10.2, purified antibody, clone 17F10.2, Chemicon®,
交差性
monkey, mouse, rat
アプリケーション
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
A8404
アミトリプチリン 塩酸塩, ≥98% (TLC), powder,
Species
human
D4526
ドキセピン 塩酸塩, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Species
human
51330
ハルマリン, ≥95%,
Species
human, rat

Small Molecule - Ligand

製品番号
詳細
Species
A138
アミノベンズトロピン, solid,
Species
human

esiRNA

製品番号
詳細
Species
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
Species
mouse