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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

別名:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-IKKa (p45) Antibody, clone 881H3, clone 881H3, from mouse,
交差性
human
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, canine, feline, human, monkey, mouse, porcine, rat
アプリケーション
affinity binding assay
immunohistochemistry

inhibition assay

western blot
Anti-phospho-IKK-α/β (pSer180/181) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-phospho-IKK-α/β (pSer176/177) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-Phospho-IKK alpha-S180 antibody produced in rabbit, ,
交差性
human, mouse
アプリケーション
western blot

Proteins

製品番号
詳細
Species
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CHUK,
Species
human
MISSION® esiRNA, targeting mouse Chuk,
Species
mouse

Small Molecule - Substrate

製品番号
詳細
Species
IKK Substrate Peptide, ,
Species
human