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Merck

CMA1

chymase 1, mast cell

別名:
CYH, MCT1, chymase
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1215) Summary: This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008]
  • Mouse(17228) chymase 1, mast cell
  • Rat(25627) chymase 1, mast cell
  • dog(490628) chymase 1, mast cell
  • domestic guinea pig(100135503) chymase 1, mast cell
  • naked mole-rat(101714600) chymase 1, mast cell
  • domestic cat(101084796) chymase 1, mast cell
  • sheep(100144428) chymase 1, mast cell

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Chymase Antibody, clone B7, clone B7, 2.4 mg/mL, Chemicon®,
交差性
human
アプリケーション
dot blot
immunohistochemistry
Anti-CMA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-Mast Cell Chymase (CMA1) antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-Chymase Antibody, clone B7, biotin conjugated, clone B7, Chemicon®, from mouse,
交差性
human
アプリケーション
dot blot
immunohistochemistry

Proteins

製品番号
詳細
Species
キマーゼ ヒト, recombinant, expressed in Pichia pastoris,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CMA1,
Species
human