COMT
catechol-O-methyltransferase
別名:
Species:
Human COMT (1312), Mouse Comt (12846), Rat Comt (24267), cow COMT (618278), domestic guinea pig Comt (100730509), domestic cat COMT (101097022), naked mole-rat Comt (101717730), chicken COMT (416783), Horse COMT (100146509), fruit fly comt (47091)
UniProtKB ID:
遺伝子ID:
- Human(1312) Summary: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
- Mouse(12846) catechol-O-methyltransferase
- Rat(24267) catechol-O-methyltransferase
- cow(618278) catechol-O-methyltransferase
- domestic guinea pig(100730509) catechol-O-methyltransferase
- domestic cat(101097022) catechol-O-methyltransferase
- naked mole-rat(101717730) catechol-O-methyltransferase
- chicken(416783) catechol-O-methyltransferase
- Horse(100146509) catechol-O-methyltransferase
- fruit fly(47091) comatose
- dog(445450) catechol-O-methyltransferase
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-Catechol O-methyltransferase/COMT Antibody, from rabbit, purified by affinity chromatography,
交差性
bovine, horse, human, porcine, rhesus macaque
アプリケーション
immunohistochemistry
western blot
western blot
抗COMT ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, rat
アプリケーション
western blot
抗COMT ウサギ宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
esiRNA
製品番号
詳細
Species