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Merck

CRYBB2

crystallin, beta B2

別名:
CCA2, CRYB2, CRYB2A, CTRCT3, D22S665
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1415) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts. [provided by RefSeq, Jul 2008]
  • Mouse(12961) crystallin, beta B2
  • Rat(25422) crystallin, beta B2
  • domestic guinea pig(100306964) crystallin, beta B2
  • Zebrafish(553182) crystallin, beta B2
  • chicken(396088) crystallin, beta B2
  • dog(486326) crystallin, beta B2
  • domestic cat(101083214) crystallin, beta B2
  • sheep(101104345) crystallin, beta B2
  • naked mole-rat(101709109) crystallin, beta B2
  • cow(287011) crystallin, beta B2
  • Domestic Rabbit(100037715) crystallin, beta B2

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CRYBB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CRYBB2,
Species
human