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Merck

DCTN2

dynactin 2 (p50)

別名:
DCTN50, DYNAMITIN, RBP50
Species:
UniProtKB ID:
遺伝子ID:
  • Human(10540) Summary: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(69654) dynactin 2
  • Rat(299850) dynactin 2 (p50)
  • Domestic Rabbit(100339187) dynactin 2 (p50)
  • cow(527201) dynactin 2 (p50)
  • dog(474415) dynactin 2 (p50)
  • domestic cat(101093950) dynactin 2 (p50)
  • chicken(395587) dynactin 2 (p50)
  • Horse(100050464) dynactin 2 (p50)
  • naked mole-rat(101713049) dynactin 2 (p50)
  • Zebrafish(394141) dynactin 2 (p50)
  • domestic guinea pig(100721002) dynactin 2 (p50)
  • sheep(101119807) dynactin 2 (p50)

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
抗DCTN2抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗DCTN2抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-DCTN2 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human DCTN2,
Species
human
MISSION® esiRNA, targeting mouse Dctn2,
Species
mouse