F10
coagulation factor X
別名:
FX, FXA
Species:
Human F10 (2159), Mouse F10 (14058), Rat F10 (29243), chicken F10 (395876), Zebrafish f10 (282670), naked mole-rat F10 (101706544), domestic guinea pig F10 (100726878), Domestic Rabbit F10 (100008647), sheep F10 (101118624), cow F10 (790178) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(2159) Summary: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq, Jul 2008]
- Mouse(14058) coagulation factor X
- Rat(29243) coagulation factor X
- chicken(395876) coagulation factor X
- Zebrafish(282670) coagulation factor X
- naked mole-rat(101706544) coagulation factor X
- domestic guinea pig(100726878) coagulation factor X
- Domestic Rabbit(100008647) coagulation factor X
- sheep(101118624) coagulation factor X
- cow(790178) coagulation factor X-like
- cow(280787) coagulation factor X
- domestic cat(101098029) coagulation factor X
- dog(476993) coagulation factor X
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Antibodies
製品番号
詳細
交差性
アプリケーション
モノクローナル抗第X因子抗体 マウス宿主抗体, clone HX-1, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
モノクローナル抗第X因子抗体 マウス宿主抗体, clone GT268, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Proteins
製品番号
詳細
Species