F7
coagulation factor VII (serum prothrombin conversion accelerator)
別名:
SPCA
Species:
Human F7 (2155), Mouse F7 (14068), Rat F7 (260320), naked mole-rat F7 (101706917), domestic guinea pig F7 (100727155), fruit fly f7 (5657732), Zebrafish f7 (114423), chicken F7 (395086), dog F7 (607661), domestic cat F7 (101090581) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(2155) Summary: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- Mouse(14068) coagulation factor VII
- Rat(260320) coagulation factor VII (serum prothrombin conversion accelerator)
- naked mole-rat(101706917) coagulation factor VII (serum prothrombin conversion accelerator)
- domestic guinea pig(100727155) coagulation factor VII (serum prothrombin conversion accelerator)
- fruit fly(5657732) f7
- Zebrafish(114423) coagulation factor VII
- chicken(395086) coagulation factor VII (serum prothrombin conversion accelerator)
- dog(607661) coagulation factor VII (serum prothrombin conversion accelerator)
- domestic cat(101090581) coagulation factor VII (serum prothrombin conversion accelerator)
- cow(617960) coagulation factor VII (serum prothrombin conversion accelerator)
- sheep(101118369) coagulation factor VII (serum prothrombin conversion accelerator)
- Domestic Rabbit(100009399) coagulation factor VII (serum prothrombin conversion accelerator)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
抗第VII因子抗体, マウスモノクロナール, clone HVII-1, purified from hybridoma cell culture,
交差性
human
アプリケーション
ELISA
western blot
western blot
Anti-Coagulation factor VIIa, from rabbit, purified by affinity chromatography,
交差性
human, primate
アプリケーション
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-FA7 (light chain, Cleaved-Arg212) antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot