コンテンツへスキップ
Merck

FGR

feline Gardner-Rasheed sarcoma viral oncogene homolog

別名:
SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2268) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14191) Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
  • Rat(79113) feline Gardner-Rasheed sarcoma viral oncogene
  • domestic cat(101083781) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • dog(487341) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • sheep(101107075) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • cow(516133) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • Horse(100056804) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • naked mole-rat(101704214) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • domestic guinea pig(100735748) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Phosphotyrosine FGR / Tyrosine-protein Kinase Fgr ELISA Kit, ,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
抗FGR抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗FGR抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ダサチニブ, ≥98% (HPLC),
Species
human
ダサチニブ, ,
Species
human

Proteins

製品番号
詳細
Species
FGR、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human FGR,
Species
human
MISSION® esiRNA, targeting mouse Fgr,
Species
mouse