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Merck

FLT1

fms-related tyrosine kinase 1

別名:
FLT, FLT-1, VEGFR-1, VEGFR1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2321) Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
  • Mouse(14254) FMS-like tyrosine kinase 1
  • Rat(54251) FMS-related tyrosine kinase 1
  • domestic guinea pig(100732326) fms-related tyrosine kinase 1
  • Zebrafish(544667) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • dog(403727) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • domestic cat(101088292) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • sheep(443088) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • chicken(374100) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Horse(100061940) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • cow(503620) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Domestic Rabbit(100343352) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Horse(100033957) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • naked mole-rat(101711333) fms-related tyrosine kinase 1

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Human VEGFR1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Rat VEGFR1 ELISA, for serum, plasma and cell culture supernatants,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
モノクローナル抗血管内皮増殖因子受容体-1抗体 マウス宿主抗体, clone FLT-11, ascites fluid,
交差性
human
アプリケーション
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-FLT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0344, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-phospho-VEGFR1 (pTyr1333) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-VEGF Receptor-1 Antibody, Chemicon®, from mouse,
交差性
human, mouse
アプリケーション
ELISA
western blot
Anti-phospho-VEGFR1 (pTyr1048) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

Small Molecule - Inhibitor

製品番号
詳細
Species
SU 4312, ≥98% (HPLC),
Species
human
SU 5416, ≥98% (HPLC),
Species
human, mouse
ラゾパニブ, ,
Species
human

Proteins

製品番号
詳細
Species
VEGFレセプター-1(Flt-1)/Fcキメラ ヒト, >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder,
Species
human
Flt1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
FLT1(784-末端), 活性型, GSTタグ付加 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human FLT1,
Species
human