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Merck

GABBR2

gamma-aminobutyric acid (GABA) B receptor, 2

別名:
GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099
Species:
Human GABBR2 (9568), Mouse Gabbr2 (242425), Rat Gabbr2 (83633), domestic guinea pig Gabbr2 (100170764), naked mole-rat Gabbr2 (101719923), Horse GABBR2 (100063963), sheep GABBR2 (101103544), Domestic Rabbit GABBR2 (100346845), domestic cat GABBR2 (101093058), cow GABBR2 (517040) ...詳細
UniProtKB ID:
O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9
遺伝子ID:
  • Human(9568) Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
  • Mouse(242425) gamma-aminobutyric acid (GABA) B receptor, 2
  • Rat(83633) gamma-aminobutyric acid (GABA) B receptor 2
  • domestic guinea pig(100170764) gamma-aminobutyric acid (GABA) B receptor, 2
  • naked mole-rat(101719923) gamma-aminobutyric acid (GABA) B receptor, 2
  • Horse(100063963) gamma-aminobutyric acid (GABA) B receptor, 2
  • sheep(101103544) gamma-aminobutyric acid (GABA) B receptor, 2
  • Domestic Rabbit(100346845) gamma-aminobutyric acid (GABA) B receptor, 2
  • domestic cat(101093058) gamma-aminobutyric acid (GABA) B receptor, 2
  • cow(517040) gamma-aminobutyric acid (GABA) B receptor, 2
  • dog(481627) gamma-aminobutyric acid (GABA) B receptor, 2
  • Zebrafish(560267) gamma-aminobutyric acid (GABA) B receptor, 2
  • chicken(420979) gamma-aminobutyric acid (GABA) B receptor, 2

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Small Molecule - Agonist

製品番号
詳細
Species
PHR1682
(±)-バクロフェン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1048200
(±)-バクロフェン, United States Pharmacopeia (USP) Reference Standard,
Species
human
B0200000
(±)-バクロフェン, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP028
(±)-バクロフェン, British Pharmacopoeia (BP) Reference Standard,
Species
human
B5399
(±)-バクロフェン, ≥98% (HPLC), solid,
Species
human, rat

Small Molecule - Antagonist

製品番号
詳細
Species
A6566
2-ヒドロキシサクロフェン, ≥98% (TLC), solid,
Species
human
P118
ファクロフェン, solid,
Species
human
B5399
(±)-バクロフェン, ≥98% (HPLC), solid,
Species
human, rat
S166
サクロフェン, solid,
Species
mouse, human, rat
A2129
γ-アミノ酪酸, ≥99%,
Species
human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
AB2255
Anti-GABA B Receptor R2 Antibody, serum, from guinea pig,
交差性
bovine, canine, chimpanzee, horse, human, mouse, rat, rhesus macaque, rhesus monkey
アプリケーション
immunohistochemistry
western blot
G9920
Anti-GABAB Receptor 2 ウサギ宿主抗体, affinity isolated antibody, lyophilized powder,
交差性
rat
アプリケーション
western blot
HPA013820
Anti-GABBR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
SAB5200418
Monoclonal Anti-Gaba-B Receptor 2 - Rpe antibody produced in mouse, clone S81-2, purified immunoglobulin,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
immunohistochemistry
western blot
AB5848
Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat, Chemicon®, from rabbit,
交差性
human, rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
N142
NO-711 塩酸塩, ≥98% (HPLC),
Species
human
V8261
(±)-ビガバトリン, ,
Species
human

esiRNA

製品番号
詳細
Species
EHU002331
MISSION® esiRNA, targeting human GABBR2,
Species
human