HP
haptoglobin
別名:
BP, HP2ALPHA2, HPA1S
Species:
Human HP (3240), Mouse Hp (15439), Rat Hp (24464), Zebrafish hp (566096), fruit fly hp (251278), domestic cat HP (100144610), dog HP (479668), Domestic Rabbit HP (100008816), sheep HP (101102413), cow HP (280692) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(15439) haptoglobin
- Rat(24464) haptoglobin
- Zebrafish(566096) haptoglobin
- fruit fly(251278) humped
- domestic cat(100144610) haptoglobin
- dog(479668) haptoglobin
- Domestic Rabbit(100008816) haptoglobin
- sheep(101102413) haptoglobin
- cow(280692) haptoglobin
- naked mole-rat(101705743) haptoglobin
- domestic guinea pig(100721435) haptoglobin
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
交差性
human
アプリケーション
ELISA
dot blot
immunoprecipitation (IP)
western blot
dot blot
immunoprecipitation (IP)
western blot
Anti-Haptoglobin (HP) antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
western blot
Proteins
esiRNA
製品番号
詳細
Species