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Merck

ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

別名:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Human Integrin alpha-M ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
抗インテグリンαM [CD11b]抗体、クローンOX-42, clone OX-42, Chemicon®, from mouse,
交差性
rat
アプリケーション
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Milli-Mark® Anti-CD11B-PE Antibody, clone 2LPM19c, clone 2LPM19c, Milli-Mark®, from mouse,
交差性
human
アプリケーション
flow cytometry
Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated, clone OX-42, Chemicon®, from mouse,
交差性
rat
アプリケーション
flow cytometry
immunohistochemistry
Anti-CD11b/CD18 Antibody, clone mAb107, clone mAb107, from mouse,
交差性
human, nonhuman primates
アプリケーション
dot blot
flow cytometry

immunohistochemistry

inhibition assay
Monoclonal Anti-CD11b antibody produced in mouse, clone ICRF44, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
flow cytometry

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human ITGAM,
Species
human
MISSION® esiRNA, targeting mouse Itgam,
Species
mouse