MADD
MAP-kinase activating death domain
別名:
DENN, IG20, RAB3GEP
Species:
Human MADD (8567), Mouse Madd (228355), Rat Madd (94193), sheep MADD (101117276), domestic guinea pig Madd (100725450), naked mole-rat Madd (101710698), cow MADD (534306), Horse MADD (100051327), domestic cat MADD (101093297), dog MADD (475982) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(8567) Summary: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(228355) MAP-kinase activating death domain
- Rat(94193) MAP-kinase activating death domain
- sheep(101117276) MAP-kinase activating death domain
- domestic guinea pig(100725450) MAP-kinase activating death domain
- naked mole-rat(101710698) MAP-kinase activating death domain
- cow(534306) MAP-kinase activating death domain
- Horse(100051327) MAP-kinase activating death domain
- domestic cat(101093297) MAP-kinase activating death domain
- dog(475982) MAP-kinase activating death domain
- chicken(423184) MAP-kinase activating death domain
- Zebrafish(100150917) MAP-kinase activating death domain
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-MADD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MADD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
KD-Validated Anti MAP Kinase Activating Death Domain Antibody, clone 24GB110, Rabbit Monoclonal, clone 24GB110, recombinant rabbit monoclonal, expressed in HEK293 cells,
交差性
human, rat
アプリケーション
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot