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Merck

MAPKAPK5

mitogen-activated protein kinase-activated protein kinase 5

別名:
MAPKAP-K5, MK-5, MK5, PRAK
Species:
UniProtKB ID:
遺伝子ID:
  • Human(8550) Summary: The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
  • Mouse(17165) MAP kinase-activated protein kinase 5
  • Rat(498183) mitogen-activated protein kinase-activated protein kinase 5
  • naked mole-rat(101703557) mitogen-activated protein kinase-activated protein kinase 5
  • cow(535625) mitogen-activated protein kinase-activated protein kinase 5
  • Zebrafish(436608) mitogen-activated protein kinase-activated protein kinase 5
  • dog(477480) mitogen-activated protein kinase-activated protein kinase 5
  • domestic guinea pig(100730794) mitogen-activated protein kinase-activated protein kinase 5
  • sheep(101116258) mitogen-activated protein kinase-activated protein kinase 5
  • domestic cat(101082699) mitogen-activated protein kinase-activated protein kinase 5
  • chicken(373929) mitogen-activated protein kinase-activated protein kinase 5
  • Horse(100057579) mitogen-activated protein kinase-activated protein kinase 5

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MAPKAPK5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
ANTI-PRAK (MAPKAPK5) (T182) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Monoclonal Anti-MAPKAPK5, (C-terminal) antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot
Monoclonal Anti-MAPKAPK5 antibody produced in mouse, clone 2D5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

Proteins

製品番号
詳細
Species
PRAK Protein, unactive, ,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MAPKAPK5,
Species
human
MISSION® esiRNA, targeting human MAPKAPK5 (2),
Species
human