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Merck

MARCH2

membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

別名:
MARCH-II, RNF172
Species:
UniProtKB ID:
遺伝子ID:
  • Human(51257) Summary: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]
  • Mouse(224703) membrane-associated ring finger (C3HC4) 2
  • Rat(362849) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • Zebrafish(555611) membrane-associated ring finger (C3HC4) 2
  • domestic guinea pig(100733733) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • domestic cat(101090087) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • cow(508949) membrane-associated ring finger (C3HC4) 2
  • dog(611624) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • naked mole-rat(101720054) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • sheep(101103806) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • chicken(420062) membrane-associated ring finger (C3HC4) 2

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-MARCH2 antibody produced in mouse, clone 7F3, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MARCH2,
Species
human