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Merck

PARN

poly(A)-specific ribonuclease

別名:
DAN
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Rat(360464) poly(A)-specific ribonuclease
  • domestic guinea pig(100732149) poly(A)-specific ribonuclease
  • naked mole-rat(101715275) poly(A)-specific ribonuclease
  • cow(524155) poly(A)-specific ribonuclease
  • Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Domestic Rabbit(100351489) poly(A)-specific ribonuclease
  • domestic cat(101100021) poly(A)-specific ribonuclease
  • dog(479839) poly(A)-specific ribonuclease
  • chicken(416423) poly(A)-specific ribonuclease
  • sheep(101112185) poly(A)-specific ribonuclease

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Mouse Parn / Poly(A)-specific Ribonuclease PARN ELISA Kit, for serum, plasma and cell culture supernatants,
Species
mouse

Antibodies

製品番号
詳細
交差性
アプリケーション
抗PARN抗体 ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗PARN抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PARN,
Species
human
MISSION® esiRNA, targeting mouse Parn,
Species
mouse